Inhibitors of the interferon response enhance virus replication in vitro. [PDF]
, 2014 This work was supported by the University of St Andrews (CSA, CES) and the Wellcome Trust (grant 087751/A/08/Z) (RER).Virus replication efficiency is influenced by two conflicting factors, kinetics of the cellular interferon (IFN) response and induction ...
Richard E. Randall +8 more
core +1 more source
Vaccines, 2022 This study was a randomized, double-blind, placebo-controlled study to evaluate the safety and viral shedding of live attenuated influenza vaccine (LAIV) in Chinese healthy juveniles and adults. A total of 80 Eligible volunteers were divided into two age
Li Li +19 more
doaj +1 more source
A live attenuated varicella vaccine
Uirusu, 2009 The vaccine virus was isolated from a vesicle of a 3-year-old otherwise healthy boy called Oka (his family name) who had typical varicella. This virus was passaged through human embryonic lung cells, guinea pig embryonic cells at a low temperature, and human diploid cells (WI-38). It was then adapted to MRC-5 human diploid cells for vaccine preparation.
openaire +3 more sources
Parenteral vaccination of mammalian livestock with Newcastle disease virus-based vector vaccines offers optimal efficacy and safety [PDF]
, 2011 Newcastle disease virus (NDV) is an avian virus that is being evaluated as a vaccine vector for the delivery of foreign genes in mammals. The use of NDV as a vaccine vector in these species offers two major advantages.
Adriaan F.G. Antonis +7 more
core +1 more source
Multivalent poultry vaccine development using Protein Glycan Coupling Technology
Microbial Cell Factories, 2021 Background Poultry is the world's most popular animal-based food and global production has tripled in the past 20 years alone. Low-cost vaccines that can be combined to protect poultry against multiple infections are a current global imperative ...
Marta Mauri +13 more
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Live vaccination tactics: possible approaches for controlling visceral leishmaniasis
Frontiers in Immunology, 2014 Vaccination with durable immunity is the main goal and fundamental to control leishmaniasis. To stimulate the immune response, small numbers of parasites are necessary to be presented in the mammalian host.
Noushin eSaljoughian +2 more
doaj +1 more source
Efficacy of mRNA Vaccines in Comparison to Live-Attenuated Vaccines
, 2021 Efficacy of mRNA Vaccines in Comparison to Live-Attenuated ...
Macintyre, Grace +2 more
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Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L
Viruses, 2022 African swine fever (ASF) is the cause of a recent pandemic that is posing a threat to much of the world swine production. The etiological agent, ASF virus (ASFV), infects domestic and wild swine, producing a variety of clinical presentations depending ...
Xuan Hanh Tran +10 more
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Immunity to Visceral Leishmaniasis Using Genetically Defined Live-Attenuated Parasites [PDF]
, 2012 Leishmaniasis is a protozoan parasitic disease endemic to the tropical and subtropical regions of the world, with three major clinical forms, self-healing cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and visceral leishmaniasis (VL ...
Angamuthu Selvapandiyan +6 more
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Attenuation and Stability of CHIKV-NoLS, a Live-Attenuated Chikungunya Virus Vaccine Candidate
Vaccines, 2018 Our previous investigation of the nucleolar localisation sequence (NoLS) of chikungunya virus (CHIKV) capsid protein demonstrated the role of capsid in CHIKV virulence.
Eranga Abeyratne +4 more
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