Results 21 to 30 of about 1,979,042 (305)
, 2023 Rotavirus vaccines have reduced effectiveness in high mortality settings. Interference between enteric viruses and live-attenuated oral vaccine strains may be a factor.
Asmaa El-Heneidy +7 more
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MicroRNA-Attenuated Virus Vaccines
Non-Coding RNA, 2018 Live-attenuated vaccines are the most effective way to establish robust, long-lasting immunity against viruses. However, the possibility of reversion to wild type replication and pathogenicity raises concerns over the safety of these vaccines. The use of
Elizabeth J. Fay, Ryan A. Langlois
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Virology Journal, 2012 Background H5N1 highly pathogenic avian influenza virus (HPAIV) is continuously circulating in many Asian countries and threatening poultry industry and human population.
Zhang Wenting +4 more
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An overview of VaxchoraTM, a live attenuated oral cholera vaccine
Human Vaccines & Immunotherapeutics, 2020 Cholera remains a public health threat among the least privileged populations and regions affected by conflicts and natural disasters. Together with Water, Sanitation and Hygiene practices, use of oral cholera vaccines (OCVs) is a key tool to prevent ...
Tarun Saluja +4 more
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Combination attenuation offers strategy for live-attenuated coronavirus vaccines [PDF]
Journal of Virology, 2018 Abstract With an ongoing threat posed by circulating zoonotic strains, new strategies are required to prepare for the next emergent coronavirus (CoV). Previously, groups had targeted conserved coronavirus proteins as a strategy to generate live-attenuated vaccine strains against current and future CoVs.
Menachery, Vineet D. +9 more
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Radiation-attenuated schistosome vaccination--a brief historical perspective. [PDF]
, 2009 The high level of protection which can be induced by vaccination of a range of hosts, from rodents to primates, with live radiation-attenuated schistosome larvae offers great promise for development of a human schistosome vaccine.
Bickle, QD, Q. D. BICKLE
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Rational Development of Live-Attenuated Zika Virus Vaccines
Pathogens, 2023 Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa, Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the neurological autoimmune disorder Guillain–Barre syndrome in adults and ...
Awadalkareem Adam +2 more
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An oral live attenuated vaccine strategy against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/2019-nCoV) [PDF]
Research Ideas and Outcomes, 2020 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/2019-nCoV) infection has become a pandemic called COVID-19. The virus binds to angiotensin converting enzyme 2 (ACE2) and TMPRSS2 which are abundantly expressed on various human cells including ...
Madhusudana Girija Sanal +1 more
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EBioMedicine, 2020 Background: Live attenuated vaccines (LAVs) can mimic natural infection and have advantages to stimulate a robust and sustained immune response as well as to confer long-term protection.
Ya-Nan Zhang +7 more
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