Results 41 to 50 of about 1,979,042 (305)

Evaluation of live-attenuated Histomonas meleagridis isolates as vaccine candidates against wild-type challenge

open access: yesPoultry Science, 2022
: Repeated serial in vitro passage of Histomonas meleagridis, the etiological agent of histomoniasis (blackhead) of turkeys, was demonstrated to markedly achieve attenuation and reduction of virulence as compared to the original wild-type isolate.
L.C. Beer   +7 more
doaj   +1 more source

Immunisation with live attenuated Salmonella dublin expressing a sporozoite protein confers partial protection against Theileria parva [PDF]

open access: yes, 1998
Cattle immunised with a recombinant form of p67, the major surface antigen of Theileria parva sporozoites, have been shown to be protected against parasite challenge. In an attempt to simplify the immunisation procedure live attenuated Salmonella strains
Duchateau, Luc   +13 more
core   +1 more source

ATTENUATED AND MODIFIED VACCINE VIRUSES: DO THEY ACTAS A SOURCE OF SOME OTHER VIRAL DISEASES? [PDF]

open access: yes, 2023
For effective control of several viral diseases, live virus vaccines are given preference over killed or inactivated vaccines for their higher immunogenic potentials.
Shibabrata Pattanayak   +1 more
core   +2 more sources

Safety and Viral Shedding of Live Attenuated Influenza Vaccine (LAIV) in Chinese Healthy Juveniles and Adults: A Phase Ⅰ Randomized, Double-Blind, Placebo-Controlled Study

open access: yesVaccines, 2022
This study was a randomized, double-blind, placebo-controlled study to evaluate the safety and viral shedding of live attenuated influenza vaccine (LAIV) in Chinese healthy juveniles and adults. A total of 80 Eligible volunteers were divided into two age
Li Li   +19 more
doaj   +1 more source

Elegant and Innovative Recoding Strategies for Advancing Vaccine Development

open access: yesVaccines
Recoding strategies have emerged as a promising approach for developing safer and more effective vaccines by altering the genetic structure of microorganisms, such as viruses, without changing their proteins.
François Meurens   +2 more
doaj   +1 more source

Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L

open access: yesViruses, 2022
African swine fever (ASF) is the cause of a recent pandemic that is posing a threat to much of the world swine production. The etiological agent, ASF virus (ASFV), infects domestic and wild swine, producing a variety of clinical presentations depending ...
Xuan Hanh Tran   +10 more
doaj   +1 more source

Live attenuated vaccines.

open access: yes, 2016
Live attenuated vaccines.
David McMurray (3213516)   +7 more
core   +1 more source

Urgent challenges in implementing live attenuated influenza vaccine. [PDF]

open access: yes, 2017
Conflicting reports have emerged about the effectiveness of the live attenuated influenza vaccine. The live attenuated influenza vaccine appears to protect particularly poorly against currently circulating H1N1 viruses that are derived from the 2009 ...
Anika Singanayagam   +7 more
core   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen   +10 more
wiley   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga   +3 more
wiley   +1 more source

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