Results 31 to 40 of about 1,979,042 (305)

A booster regime of liposome-delivered live-attenuated CHIKV vaccine RNA genome protects against chikungunya virus disease in mice

, 2023
Mosquito-transmitted chikungunya virus (CHIKV) is the causal pathogen of CHIKV disease and is responsible for global epidemics of arthritic disease. CHIKV infection can lead to severe chronic and debilitating arthralgia, significantly impacting patient ...
Abeyratne, E, Yang, C, Liu, X, Shambhavi Rao, Ali Zaid, Helen Mostafavi, Zaid, A, Rao, S, Freitas, JR, Tharmarajah, K, Kothila Tharmarajah, Adam Taylor, Mehfuz Zaman, Xiang Liu, Mostafavi, H, Suresh Mahalingam, Zaman, M, Joseph R. Freitas, Eranga Abeyratne, Mahalingam, S, Chenying Yang, Taylor, A   +21 more
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Exchange of the C-terminal part of VP3 from very virulent infectious bursal disease virus results in an attenuated virus with a unique antigenic structure [PDF]

, 2002
Infectious bursal disease virus (IBDV) is the major viral pathogen in the poultry industry. Live attenuated serotype 1 vaccine strains are commonly used to protect susceptible chickens during their first 6 weeks of life. Wild-type serotype 1 IBDV strains
Peeters, B.P.H., ter Huurne, A.A.H.M., Pol, J.M., Hoekman, A.J.W., Huurne, A.A.H.M., ter, Boot, H.J., Gielkens, A.L.J.   +6 more
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Preparation Of Live Attenuated Vaccine Against Strangles

The Iraqi Journal of Veterinary Medicine, 2007
Live attenuated vaccine of Strept. Equi was prepared by culturing the bacterium in increasing concentration of acriflavin and the vaccine was given by installation in the nose of rabbits.
M. M. Kaisium
doaj   +1 more source

The use of attenuated isolates of Pepino mosaic virus for cross-protection [PDF]

, 2010
Pepino mosaic virus (PepMV) has recently emerged as a highly infectious viral pathogen in tomato crops. Greenhouse trials were conducted under conditions similar to commercial tomato production.
Schenk, M.F., Vermunt, A.M.W., Hamelink, R., Vlugt, R.A.A., van der, Kaarsemaker, R.C., Stijger, C.C.M.M., van der Vlugt, R.A.A.   +6 more
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Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines

mBio, 2019
Nonstructural protein 1 (NS1) of influenza virus is a key virulence element with multifunctional roles in virus replication and a potent antagonist of host immune response.
Pui Wang, Min Zheng, Siu-Ying Lau, Pin Chen, Bobo Wing-Yee Mok, Siwen Liu, Honglian Liu, Xiaofeng Huang, Conor J. Cremin, Wenjun Song, Yixin Chen, Yik-Chun Wong, Haode Huang, Kelvin Kai-Wong To, Zhiwei Chen, Ningshao Xia, Kwok-Yung Yuen, Honglin Chen   +17 more
doaj   +1 more source

Herpes zoster following COVID-19 vaccination in an immunocompetent and vaccinated for herpes zoster adult: A two-vaccine related event?

Metabolism Open, 2022
Reactivation of varicella-zoster virus (VZV) has been reported after the administration of different vaccine platforms against SARS-CoV-2, also among individuals without known immunosuppressive states.
Natalia G. Vallianou, Dimitrios Tsilingiris, Irene Karampela, Junli Liu, Maria Dalamaga   +4 more
doaj   +1 more source

Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding. [PDF]

, 2021
Safe and effective vaccines are urgently needed to stop the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We construct a series of live attenuated vaccine candidates by large-scale recoding of the SARS-CoV-2 genome and ...
Trimpert, Jakob, Adler, Julia M, Abdelgawad, Azza, Höfler, Thomas, Firsching, Theresa C, Labroussaa, Fabien, Kaufer, Susanne, Thiel, Volker, Vladimirova, Daria, Kunec, Dusan, Ebert, Nadine, Conradie, Andelé, Dietert, Kristina, Tran, Thi Nhu Thao, Bertzbach, Luca D, Jores, Jörg, Gruber, Achim D, Osterrieder, Nikolaus   +17 more
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Protective efficacy and DIVA potential of a

Poultry Science
Salmonella Enteritidis poses a significant threat to poultry health and production, leading to substantial economic losses worldwide. Transmission through contaminated poultry products poses a continuous risk to public health.
Yanyu Ruan, Xilong Kang, Zeyun Lin, Tianlong Sun, Zhiming Pan, Xinwei Wang, Tingting Pan, Yimeng Zhao, Hongqin Song   +8 more
doaj   +1 more source

Attenuation of the influenza virus by microRNA response element in vivo and protective efficacy against 2009 pandemic H1N1 virus in mice

International Journal of Infectious Diseases, 2015
Background: The 2009 influenza pandemics underscored the need for effective vaccines to block the spread of influenza virus infection. Most live attenuated vaccines utilize cold-adapted, temperature-sensitive virus.
Chunlai Feng, Mingming Tan, Wenkui Sun, Yi Shi, Zheng Xing   +4 more
doaj   +1 more source

Multivalent poultry vaccine development using Protein Glycan Coupling Technology

Microbial Cell Factories, 2021
Background Poultry is the world's most popular animal-based food and global production has tripled in the past 20 years alone. Low-cost vaccines that can be combined to protect poultry against multiple infections are a current global imperative ...
Marta Mauri, Thippeswamy H. Sannasiddappa, Prerna Vohra, Ricardo Corona-Torres, Alexander A. Smith, Cosmin Chintoan-Uta, Abi Bremner, Vanessa S. Terra, Sherif Abouelhadid, Mark P. Stevens, Andrew J. Grant, Jon Cuccui, Brendan W. Wren, the Glycoengineering of Veterinary Vaccines Consortium   +13 more
doaj   +1 more source