Results 171 to 180 of about 99,732 (351)

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Attenuated African swine fever viruses and the live vaccine candidates: a comprehensive review

Microbiology Spectrum
The African swine fever virus (ASFV) is spreading worldwide and causing huge economic losses to the global pig industry. The ASFV genome is 170–193 kb in length, contains approximately 150 open reading frames, and encodes more than 200 proteins, most of ...
Jiaqi Fan, Haisheng Yu, Faming Miao, Junnan Ke, Rongliang Hu   +4 more
doaj   +1 more source

A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice. [PDF]

Nat Commun, 2022
Lee A, Scott MKD, Wimmers F, Arunachalam PS, Luo W, Fox CB, Tomai M, Khatri P, Pulendran B.   +8 more
europepmc   +1 more source

Additional file 9: Table S5. of The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles

, 2015
Y. Tarabichi, K B Li, S. Hu, C. Nguyen, X. W. Wang, D. Elashoff, K. Saira, Bryan Frank, Monika Bihan, E. Ghedin, Barbara MethĂŠ, Jane C. Deng   +11 more
openalex   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Should the world collaborate imminently to develop neglected live-attenuated vaccines for COVID-19? [PDF]

J Med Virol, 2022
Chen JM.
europepmc   +1 more source

A Phase 1 Randomized Placebo-Controlled Study to Assess the Safety, Immunogenicity and Genetic Stability of a New Potential Pandemic H7N9 Live Attenuated Influenza Vaccine in Healthy Adults [PDF]

, 2020
Irina Kiseleva, Irina Isakova–Sivak, Marina Stukova, Marianna Erofeeva, Svetlana Donina, Natalie Larionova, Elena Krutikova, Ekaterina Bazhenova, Ekaterina Stepanova, Kirill Vasilyev, Victoria Matyushenko, Marina A. Krylova, Julia Galatonova, Aleksey Ershov, Dmitry Lioznov, Erin Sparrow, Guido Torelli, Larisa Rudenko   +17 more
openalex   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Genome Plasticity of African Swine Fever Virus: Implications for Diagnostics and Live-Attenuated Vaccines. [PDF]

Pathogens, 2022
Faburay B.
europepmc   +1 more source