Commercial PRRS Modified-Live Virus Vaccines
Vaccines, 2021 Porcine reproductive and respiratory syndrome (PRRS) virus (PRRSV) presents one of the challenging viral pathogens in the global pork industry. PRRS is characterized by two distinct clinical presentations; reproductive failure in breeding animals (gilts,
Chanhee Chae
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Formulation of a live bacterial vaccine for stable room temperature storage results in loss of acid, bile and bile salt resistance [PDF]
, 2008 Live bacterial vaccines have great promise both as vaccines against enteric pathogens and as heterologous antigen vectors against diverse diseases. Ideally, room temperature stable dry formulations of live bacterial vaccines will allow oral vaccination ...
Edwards, Alexander D. +1 more
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Live vaccination tactics: possible approaches for controlling visceral leishmaniasis
Frontiers in Immunology, 2014 Vaccination with durable immunity is the main goal and fundamental to control leishmaniasis. To stimulate the immune response, small numbers of parasites are necessary to be presented in the mammalian host.
Noushin eSaljoughian +2 more
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Outside in – inside out. Creating focus on the patient – a vaccine company perspective
Human Vaccines & Immunotherapeutics, 2018 Involving patients in the development of medicines and vaccines should result in benefits to patients. The vaccine recipient is usually a healthy person.
Denis Sohy +7 more
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Bulletin of the National Research Centre, 2020 Background Poultry bacterial pathogens are mainly controlled by using high-cost sanitary measures and medical treatment. However, the drug-resistant strains of pathogens continuously emerge, and medical treatments are often ineffective.
Nagwa S. Rabie, Zeinab M. S. Amin Girh
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The effect of diatomaceous earth in live, attenuated infectious bronchitis vaccine, immune responses, and protection against challenge. [PDF]
, 2017 Live virus vaccines are commonly used in poultry production, particularly in broilers. Massive application and generation of a protective local mucosal and humoral immunity with no adverse effects is the main goal for this strategy.
Corbeil, Lynette B +3 more
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Perspectives of Next-Generation Live-Attenuated Rift Valley Fever Vaccines for Animal and Human Use
Vaccines, 2023 Live-attenuated Rift Valley fever (RVF) vaccines transiently replicate in the vaccinated host, thereby effectively initiating an innate and adaptive immune response.
Paul J. Wichgers Schreur +4 more
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Biomarkers of Safety and Immune Protection for Genetically Modified Live Attenuated Leishmania Vaccines Against Visceral Leishmaniasis – Discovery and Implications [PDF]
, 2014 Despite intense efforts there is no safe and efficacious vaccine against visceral leishmaniasis, which is fatal and endemic in many tropical countries. A major shortcoming in the vaccine development against blood borne parasitic agents such as Leishmania
Angamuthu Selvapandiyan +5 more
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Live bacterial vaccines – a review and identification of potential hazards
Microbial Cell Factories, 2006 The use of live bacteria to induce an immune response to itself or to a carried vaccine component is an attractive vaccine strategy. Advantages of live bacterial vaccines include their mimicry of a natural infection, intrinsic adjuvant properties and ...
Detmer Ann, Glenting Jacob
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Live Bacterial Prophylactics in Modern Poultry
Frontiers in Veterinary Science, 2020 Commercial poultry farms frequently use live bacterial prophylactics like vaccines and probiotics to prevent bacterial infections. Due to the emergence of antibiotic-resistant bacteria in poultry animals, a closer examination into the health benefits and
Graham A. J. Redweik +5 more
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