Results 21 to 30 of about 7,374,862 (391)

Liver Transplantation for Pediatric Liver Cancer [PDF]

Cancers, 2020
Unresectable hepatocellular carcinoma (HCC) was first removed successfully with total hepatectomy and liver transplantation (LT) in a child over five decades ago. Since then, children with unresectable liver cancer have benefitted greatly from LT and a confluence of several equally important endeavors. Regional and trans-continental collaborations have
Rakesh Sindhi, Vinayak Rohan, Andrew Bukowinski, Sameh Tadros, Jean de Ville de Goyet, Louis Rapkin, Sarangarajan Ranganathan   +6 more
openaire   +3 more sources

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Ca, 2021
This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer.
H. Sung, J. Ferlay, R. Siegel, M. Laversanne, I. Soerjomataram, A. Jemal, F. Bray   +6 more
semanticscholar   +1 more source

Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experience

Journal of Translational Medicine, 2020
Background The genomic alterations of intrahepatic cholangiocarcinoma (ICC) in the Chinese population have not been fully revealed. Molecular profiling may provide a reference for clinical management, especially targeted therapy.
Longrong Wang, Hongxu Zhu, Yiming Zhao, Qi Pan, Anrong Mao, Weiping Zhu, Ning Zhang, Zhenhai Lin, Jiamin Zhou, Yilin Wang, Yongfa Zhang, Miao Wang, Yun Feng, Xigan He, Weiqi Xu, Lu Wang   +15 more
doaj   +1 more source

Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis

Cell Death and Disease, 2023
Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epigenetic ...
Xiao-Jun Guo, Xiao-Yong Huang, Xuan Yang, Jia-Cheng Lu, Chuan-Yuan Wei, Chao Gao, Yan-Zi Pei, Yi Chen, Qi-Man Sun, Jia-Bin Cai, Jian Zhou, Jia Fan, Ai-Wu Ke, Yujiang G. Shi, Ying-Hao Shen, Peng-Fei Zhang, Guo-Ming Shi, Guo-Huan Yang   +17 more
doaj   +1 more source

Peritumoral plasmacytoid dendritic cells predict a poor prognosis for intrahepatic cholangiocarcinoma after curative resection

Cancer Cell International, 2020
Background Plasmacytoid dendritic cells (pDCs) are present in various primary and metastatic human neoplasms; however, their clinical significance in intrahepatic cholangiocarcinoma is not clear.
Zhi-Qiang Hu, Zheng-Jun Zhou, Chu-Bin Luo, Hao-Yang Xin, Jia Li, Song-Yang Yu, Shao-Lai Zhou   +6 more
doaj   +1 more source

Adjuvant Transarterial chemoembolization does not influence recurrence-free or overall survival in patients with combined hepatocellular carcinoma and Cholangiocarcinoma after curative resection: a propensity score matching analysis

BMC Cancer, 2020
Background The prognosis of patients with combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma (CHC) is usually poor, and effective adjuvant therapy is missing making it important to investigate whether these patients may benefit from ...
Wei-Ren Liu, Meng-Xin Tian, Chen-Yang Tao, Zheng Tang, Yu-Fu Zhou, Shu-Shu Song, Xi-Fei Jiang, Han Wang, Pei-Yun Zhou, Wei-Feng Qu, Yuan Fang, Zhen-Bin Ding, Jian Zhou, Jia Fan, Ying-Hong Shi   +14 more
doaj   +1 more source

2018 Korean Liver Cancer Association-National Cancer Center Korea Practice Guidelines for the Management of Hepatocellular Carcinoma

Gut and Liver, 2019
Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection is high in middle-aged and elderly patients.
KLCA Korean Liver Cancer Association, NCC National Cancer Center   +1 more
doaj   +1 more source

Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma

World Journal of Surgical Oncology, 2023
Background CD73 promotes progression in several malignancies and is considered as a novel immune checkpoint. However, the function of CD73 in intrahepatic cholangiocarcinoma (ICC) remains uncertain.
Bao-Ye Sun, Zhang-Fu Yang, Zhu-Tao Wang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Wei Gan, Yong Yi, Shuang-Jian Qiu   +9 more
doaj   +1 more source

Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: a single-center, single-arm, phase 2 study

Signal Transduction and Targeted Therapy, 2023
Advanced intrahepatic cholangiocarcinoma (ICC) has a dismal prognosis. Here, we report the efficacy and safety of combining toripalimab, lenvatinib, and gemcitabine plus oxaliplatin (GEMOX) as first-line therapy for advanced ICC.
Guo-Ming Shi, Xiao-Yong Huang, Dong Wu, Hui-Chuan Sun, Fei Liang, Yuan Ji, Yi Chen, Guo-Huan Yang, Jia-Cheng Lu, Xian-Long Meng, Xin-Ying Wang, Lei Sun, Ning-Ling Ge, Xiao-Wu Huang, Shuang-Jian Qiu, Xin-Rong Yang, Qiang Gao, Yi-Feng He, Yang Xu, Jian Sun, Zheng-Gang Ren, Jia Fan, Jian Zhou   +22 more
doaj   +1 more source

Capecitabine and temozolomide for metastatic intermediate to high-grade pancreatic neuroendocrine neoplasm: a single center experience [PDF]

The Korean Journal of Internal Medicine, 2022
Background/Aims The combination of capecitabine and temozolomide (CAPTEM) is one of the treatment options for metastatic pancreatic neuroendocrine neoplasms (pNENs).
Sathathone Douangprachanh, Hyun Jin Joo, Hyeong Min Park, Nayoung Han, Hye Young Jang, Young Hwan Koh, Tae Hyun Kim, Sung-Sik Han, Sang-Jae Park, Woo Jin Lee, Sang Myung Woo, Jung Won Chun   +11 more
doaj   +1 more source