Results 21 to 30 of about 385,913 (358)

Liver cirrhosis [PDF]

open access: yesPostgraduate Medical Journal, 1998
Summary Liver fibrosis and its related complications continue to represent a significant worldwide healthcare burden. Over the past decade there has been considerable improvement in our understanding of the cellular mechanisms and pathophysiology underlying hepatic fibrosis.
E J, Williams, J P, Iredale
openaire   +2 more sources

Right Heart Remodeling in Patients with End-Stage Alcoholic Liver Cirrhosis: Speckle Tracking Point of View [PDF]

open access: yes, 2019
BACKGROUND: Data regarding cardiac remodeling in patients with alcoholic liver cirrhosis are scarce. We sought to investigate right atrial (RA) and right ventricular (RV) structure, function, and mechanics in patients with alcoholic liver cirrhosis.
Braun, Alexander   +8 more
core   +1 more source

Adipokines in Liver Cirrhosis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2017
Liver fibrosis can progress to cirrhosis, which is considered a serious disease. The Child-Pugh score and the model of end-stage liver disease score have been established to assess residual liver function in patients with liver cirrhosis. The development of portal hypertension contributes to ascites, variceal bleeding and further complications in these
Buechler, Christa   +3 more
openaire   +3 more sources

Regression of liver fibrosis: evidence and challenges

open access: yesChinese Medical Journal, 2020
. It has been reported that liver fibrosis could be reversed after eliminating liver injuries. This article systematically summarizes the evidence of fibrosis regression based on histology, liver stiffness, and serum biomarkers, and discusses several ...
Ya-Meng Sun   +3 more
doaj   +1 more source

Clinical characteristics and therapeutic response of immunoglobulin G4-related disease: a retrospective study of 127 Chinese patients

open access: yesOrphanet Journal of Rare Diseases, 2022
Background and aims Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition. The aim of the present study was to characterize the clinical features and therapeutic response of patients with IgG4-RD and identify risk ...
Wen An   +16 more
doaj   +1 more source

Impact of spider nevus and subcutaneous collateral vessel of chest/abdominal wall on outcomes of liver cirrhosis

open access: yesArchives of Medical Science, 2019
Introduction Spider nevus and subcutaneous collateral vessel of the chest/abdominal wall are common in liver cirrhosis. This prospective study aimed to evaluate the impact of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall on ...
Hongyu Li   +5 more
doaj   +1 more source

Pipeline for precise insoluble matrisome coverage in tissue extracellular matrices

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
The extracellular matrix (ECM) is assembled by hundreds of proteins orchestrating tissue patterning and surrounding cell fates via the mechanical–biochemical feedback loop.
Wei Chen   +11 more
doaj   +1 more source

Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]

open access: yes, 2016
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia   +5 more
core   +1 more source

IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma

open access: yesAdvanced Science, 2021
Intrahepatic cholangiocarcinoma (ICC) is highly heterogeneous. Here, the authors perform exome sequencing and bulk RNA sequencing on 73 tumor regions from 14 ICC patients to portray the multi‐faceted intratumor heterogeneity (ITH) landscape of ICC.
Xiao Xiang   +14 more
doaj   +1 more source

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