Results 31 to 40 of about 1,999,014 (306)

Leaky Gut and Gut-Liver Axis in Liver Cirrhosis: Clinical Studies Update

open access: yesGut and Liver, 2020
Portal blood flows into the liver containing the gut microbiome and its products such as endotoxin and bacterial DNA. The cirrhotic liver acts and detoxifies as the initial site of microbial products.
H. Fukui
semanticscholar   +1 more source

Resolving the fibrotic niche of human liver cirrhosis at single cell level

open access: yesNature, 2019
Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available.
P. Ramachandran   +35 more
semanticscholar   +1 more source

Right Heart Remodeling in Patients with End-Stage Alcoholic Liver Cirrhosis: Speckle Tracking Point of View [PDF]

open access: yes, 2019
BACKGROUND: Data regarding cardiac remodeling in patients with alcoholic liver cirrhosis are scarce. We sought to investigate right atrial (RA) and right ventricular (RV) structure, function, and mechanics in patients with alcoholic liver cirrhosis.
Braun, Alexander   +8 more
core   +1 more source

Liver cirrhosis [PDF]

open access: yesPostgraduate Medical Journal, 1998
Summary Liver fibrosis and its related complications continue to represent a significant worldwide healthcare burden. Over the past decade there has been considerable improvement in our understanding of the cellular mechanisms and pathophysiology underlying hepatic fibrosis.
E J, Williams, J P, Iredale
openaire   +2 more sources

Chinese guidelines on the management of liver cirrhosis (abbreviated version)

open access: yesWorld Journal of Gastroenterology, 2020
Based on reviews of the literature and experts’ consensus, the Chinese Society of Hepatology developed guidelines for the diagnosis and treatment of liver cirrhosis, in order to improve clinical practice.
Xiaoyuan Xu   +9 more
semanticscholar   +1 more source

Spontaneous porto-systemic shunts in liver cirrhosis: Clinical and therapeutical aspects

open access: yesWorld Journal of Gastroenterology, 2020
Spontaneous porto-systemic shunts (SPSS) are frequent in liver cirrhosis and their prevalence increases as liver function deteriorates, probably as a consequence of worsening portal hypertension, but without achieving an effective protection against ...
S. Nardelli   +5 more
semanticscholar   +1 more source

Impact of spider nevus and subcutaneous collateral vessel of chest/abdominal wall on outcomes of liver cirrhosis

open access: yesArchives of Medical Science, 2019
Introduction Spider nevus and subcutaneous collateral vessel of the chest/abdominal wall are common in liver cirrhosis. This prospective study aimed to evaluate the impact of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall on ...
Hongyu Li   +5 more
doaj   +1 more source

Regression of liver fibrosis: evidence and challenges

open access: yesChinese Medical Journal, 2020
. It has been reported that liver fibrosis could be reversed after eliminating liver injuries. This article systematically summarizes the evidence of fibrosis regression based on histology, liver stiffness, and serum biomarkers, and discusses several ...
Ya-Meng Sun   +3 more
doaj   +1 more source

Clinical characteristics and therapeutic response of immunoglobulin G4-related disease: a retrospective study of 127 Chinese patients

open access: yesOrphanet Journal of Rare Diseases, 2022
Background and aims Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition. The aim of the present study was to characterize the clinical features and therapeutic response of patients with IgG4-RD and identify risk ...
Wen An   +16 more
doaj   +1 more source

Pipeline for precise insoluble matrisome coverage in tissue extracellular matrices

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
The extracellular matrix (ECM) is assembled by hundreds of proteins orchestrating tissue patterning and surrounding cell fates via the mechanical–biochemical feedback loop.
Wei Chen   +11 more
doaj   +1 more source

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