Results 111 to 120 of about 1,080,361 (316)

A One Dimensional (1D) Computational Fluid Dynamics Study of Fontan-Associated Liver Disease (FALD) [PDF]

open access: yesarXiv
Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically survive into adulthood, they have reduced cardiac output due to their univentricular physiology (i.e., a Fontan ...
arxiv  

The Treatment of Liver Disease

open access: yesAJN, American Journal of Nursing, 1953
LVER disease is increasing. Whereas previously it was seen mostly in conjunction with alcoholism or malnutrition, or as a complication of cholecystitis and cholelithiasis, additional causative factors are recognized today. The wide spread epidemic hepatitis of World War II, for instance, produced a sporadic inoculation of persons hitherto never exposed
openaire   +6 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

AMMONIUM TOLERANCE IN LIVER DISEASE: OBSERVATIONS BASED ON CATHETERIZATION OF THE HEPATIC VEINS [PDF]

open access: bronze, 1955
Laurens P. White   +4 more
openalex   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

CT-based Anomaly Detection of Liver Tumors Using Generative Diffusion Prior [PDF]

open access: yesarXiv
CT is a main modality for imaging liver diseases, valuable in detecting and localizing liver tumors. Traditional anomaly detection methods analyze reconstructed images to identify pathological structures. However, these methods may produce suboptimal results, overlooking subtle differences among various tissue types.
arxiv  

THE LIPIDS OF SERUM AND LIVER IN PATIENTS WITH HEPATIC DISEASES 1 [PDF]

open access: bronze, 1945
Evelyn B. Man   +3 more
openalex   +1 more source

Alcoholic Liver Disease

open access: yesMedical Clinics of North America, 1989
Alcohol has been implicated in the genesis of liver disease for centuries. Significant progress has been made in our understanding of the pathogenesis of ALD. It is now apparent that both the consumption and the metabolism of alcohol promote the production of inflammatory mediators (cytokines) that result in hepatotoxicity and fibrogenesis.
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

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