Results 41 to 50 of about 12,320,543 (412)

Role and Mechanisms of Mitophagy in Liver Diseases

Cells, 2020
The mitochondrion is an organelle that plays a vital role in the regulation of hepatic cellular redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both acute and chronic liver diseases with emerging evidence indicating ...
Xiaowen Ma, Tara McKeen, Jianhua Zhang, W. Ding   +3 more
semanticscholar   +1 more source

Cholangiocytes: Cell transplantation [PDF]

, 2017
Background:Due to significant limitations to the access to orthotropic liver transplantation, cell therapies forliver diseases have gained large interest worldwide.Scope of review:To revise current literature dealing with cell therapy for liver diseases.
Alvaro, Domenico, Bragazzi, MARIA CONSIGLIA, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Ridola, Lorenzo   +5 more
core   +1 more source

Changes in Glutathione Content in Liver Diseases: An Update

Antioxidants, 2021
Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important thiol reducing agent involved in the modulation of redox processes.
M. Vairetti, L. G. Di Pasqua, M. Cagna, P. Richelmi, A. Ferrigno, C. Berardo   +5 more
semanticscholar   +1 more source

Serum procalcitonin levels associate with Clostridioides difficile infection in patients with inflammatory bowel disease

BMC Infectious Diseases, 2021
Background Clostridioides difficile infection (CDI) is a major cause of morbidity among patients with inflammatory bowel disease (IBD). Diagnostic biomarkers for early detection of CDI are needed in clinical practice.
Mohammad Abdehagh, Masoumeh Azimirad, Hamidreza Houri, Banafsheh Nadalian, Fahimeh Azimirad, Meysam Olfatifar, Ome Kolsoum Nasir Shoeibi, Abbas Yadegar, Shabnam Shahrokh, Mehran Mahdavi Roshan, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali   +11 more
doaj   +1 more source

Endoscopic retrograde cholangiopancreatography services in Sudan during wartime: Innovations in crisis

Endoscopy International Open
​Endoscopic retrograde cholangiopancreatography (ERCP) services in Africa have expanded in recent years, aiming to enhance healthcare infrastructure. ERCP, combining endoscopy and fluoroscopy, diagnoses and treats biliary and pancreatic ductal system ...
Abdelmounem Abdo, Salah Dafalla, Mohammed Bushra, Rodwan Mustafa, Reem Hamad, Ahmed Rafei, Mohamed Jaafer, Rawan Bidab, Waleed Gamus Ojan, Mohammed Ganim, Hala Abdalla   +10 more
doaj   +1 more source

YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation [PDF]

, 2019
Yes-associated protein (YAP) is a transcriptional co-factor involved in many cell processes, including development, proliferation, stemness, differentiation, and tumorigenesis.
Amicone, Laura, Battistelli, Cecilia, Cicchini, Carla, Consalvi, Veronica, Cozzolino, Angela Maria, Marchetti, Alessandra, Noce, Valeria, Strippoli, Raffaele, Tripodi, Marco   +8 more
core   +1 more source

Diagnosis and Management of Autoimmune Hepatitis in Adults and Children: 2019 Practice Guidance and Guidelines From the American Association for the Study of Liver Diseases

Hepatology, 2019
The objectives of this document are to provide guidance in the diagnosis and management of autoimmune hepatitis (AIH) based on current evidence and expert opinion, and to present guidelines to clinically relevant questions based on systematic reviews of ...
C. Mack, D. Adams, D. Assis, N. Kerkar, M. Manns, M. Mayo, J. Vierling, Mouaz Alsawas, M. Murad, A. Czaja   +9 more
semanticscholar   +1 more source

Population screening for liver fibrosis: Toward early diagnosis and intervention for chronic liver diseases

Hepatology, 2021
Cirrhosis, highly prevalent worldwide, develops after years of hepatic inflammation triggering progressive fibrosis. Currently, the main etiologies of cirrhosis are non‐alcoholic fatty liver disease and alcohol‐related liver disease, although chronic ...
P. Ginés, L. Castéra, F. Lammert, I. Graupera, Miquel Serra-Burriel, A. Allen, V. Wong, Phillipp Hartmann, M. Thiele, L. Caballería, R. D. de Knegt, I. Grgurević, S. Augustin, E. Tsochatzis, J. Schattenberg, I. Guha, A. Martini, R. Morillas, M. García-Retortillo, H. D. de Koning, N. Fabrellas, J. Pich, A. Ma, Mª Alba Diaz, D. Roulot, P. Newsome, M. Manns, P. Kamath, A. Krag   +28 more
semanticscholar   +1 more source

IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ß pathway

Diagnostic Pathology, 2022
Aims and background IFI16 plays an important role in innate immunity against invasive microbial infection by sensing double-stranded DNA viruses due to caspase-1-dependent inflammasome activation and subsequent maturation and secretion of IL-1β. However,
Li Liu, Shuangshuang Xie, Cheng Li, Yue Guo, Xiaoyan Liu, Xiuhua Zhao, Qiang Li, Wenjun Du   +7 more
doaj   +1 more source

Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]

, 2016
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou, Alvarez, Block, Boonstra, Deneau, Dotson, Faubion, Feldstein, Goyal, Gregorio, Halliday, Hirschfield, Hov, Jose, Jose, Levine, Levine, Liberal, Loftus, Loftus, Lundqvist, Maggiore, Malaty, Mieli-Vergani, Navaneethan, Noble-Jamieson, Olsson, Ordonez, Penna, Rönnblom, Sokol, Zholudev   +31 more
core   +1 more source