Results 61 to 70 of about 12,320,543 (412)
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
BMC GastroenterologyBackground Periampullary diverticulum (PAD) is an incidental finding during endoscopic retrograde cholangiopancreatography (ERCP), occurring more frequently in elderly patients. The influence of PAD on the ERCP procedure has been a subject of debate. The
Erfan Arabpour +5 more
doaj +1 more source
Is porto sinusoidal vascular disease to be actively searched in patients with portal vein thrombosis? [PDF]
, 2019 Porto sinusoidal vascular liver disease (PSVD) and portal vein thrombosis (PVT) are distinct vascular liver diseases characterized, respectively, by an intrahepatic and a prehepatic obstacle to the flow in the liver portal system. PVT may also occur as a
D'Amati, G. +4 more
core +1 more source
Lipoproteins in Liver Disease [PDF]
Clinical Chemistry and Laboratory Medicine, 1987 Liver disease is associated with profound and characteristic changes in lipoprotein composition and metabolism. The most pronounced alterations are the formation of lipoprotein-X in intra- and extrahepatic cholestasis, the decrease of apolipoproteins A-I and A-II and the increase of apolipoprotein E.
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
BMC Infectious Diseases, 2019 Background To evaluate the efficacy and safety of telbivudine in chronic hepatitis B women during the second and third trimesters of pregnancy. Methods The week 12–34 of pregnant women were screened in this prospective non-intervention study, with HBV ...
Li-fen Han +9 more
doaj +1 more source
Chinese Medicine, 2021 Background Weifuchun (WFC), a Chinese herbal prescription consisting of Red Ginseng, Isodon amethystoides and Fructus Aurantii, is commonly used in China to treat a variety of chronic stomach disorders. The aim of the paper was to determine the effect of
Yanqin Bian +15 more
doaj +1 more source
Current Status of Herbal Medicines in Chronic Liver Disease Therapy: The Biological Effects, Molecular Targets and Future Prospects [PDF]
, 2015 Chronic liver dysfunction or injury is a serious health problem worldwide. Chronic liver disease involves a wide range of liver pathologies that include fatty liver, hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma.
Feng, Y +5 more
core +2 more sources
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Acta Medica Iranica, 2022 There is insufficient data about esophageal body dysmotility in patients with refractory gastroesophageal reflux disease (RGERD) who have inadequate response to proton pump inhibitors (PPIs) treatment.
Asghar Bagherzadeh +3 more
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