Results 31 to 40 of about 540,924 (207)

Drug-related problems and dosage adjustment in patients with liver disease [PDF]

open access: yes, 2012
The liver is essential for the metabolism of medicinal substances. Liver disease, especially liver cirrhosis, may lead to various pharmacokinetic and pharmacodynamic changes, predisposing patients with liver cirrhosis to adverse drug events (ADEs).
Franz, Carmen Carina
core   +1 more source

The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1. [PDF]

open access: yes, 2014
BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1 ...
Ma, Jinfeng   +50 more
core   +1 more source

Pattern of liver enzymes and maternal outcome in eclamptic patients admitted to the Intensive Care Unit, University College Hospital, Nigeria

open access: yes, 2023
Introduction: Eclampsia, a hypertensive disorder, is one of the leading causes of maternal mortality in developing countries like Nigeria. We evaluated the relationship between the pattern of liver enzymes and maternal mortality in eclamptic women ...
Olusola Idowu, Oluwasomidoyin Bello
core   +1 more source

In silico Characterization of Toxicophores Found in Lemongrass (Cymbopogon citratus) and its Molecular Interaction with Kidney and Liver Enzymes

open access: yesJournal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2023
BACKGROUND OF THE STUDY: Cymbopogon citratus (lemongrass) is known for its various therapeutic claims. However, the abuse and misuse of herbal medicine is not uncommon.
John Sylvester B. Nas   +9 more
doaj   +1 more source

Insulin sensitisers in the treatment of non-alcoholic fatty liver disease : a systematic review [PDF]

open access: yes, 2011
Non-alcoholic fatty liver disease (NAFLD) is closely linked with obesity and the prevalence of NAFLD is about 17% to 33% in the Western world. There is a strong association of NAFLD with insulin resistance and, hence, insulin sensitisers have been tried.
C Clar   +21 more
core   +1 more source

Intracellular proteolytic enzymes of liver [PDF]

open access: yesExperimental Biology and Medicine, 1910
The influence of reaction upon autolysis of animal tissues has been exhaustively studied. All observers agree upon the favorable influence of a weak acid medium, and upon the inhibitory effect alkaline reaction. As an example of the influence of reaction upon autolysis, 2.5 grams of liver after five days at 37 degrees yield the following equivalents of
openaire   +2 more sources

LIVER ENZYMES

open access: yesThe Professional Medical Journal, 2015
Objective: To study the effect of breast cancer treatment on liver enzymes indiabetic and cardiac breast cancer females. Study Design: Cross-sectional type of study.Setting: Liaquat National Hospital Karachi. Period: January 2008 to January 2010. Patientsand Methods: Total 47 breast cancer patients.
Uzma Raza   +2 more
openaire   +2 more sources

Glucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease [PDF]

open access: yes, 2011
The polymorphism, KLF6-IVS1-27A, in the Krüppel-like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is associated with delayed histological progression of nonalcoholic fatty liver disease (NAFLD).
Gastaldelli, Amalia   +80 more
core   +1 more source

Deciphering the role of liver metabolic enzymes in dementia pathogenesis

open access: yesCell Investigation
The relationship between liver metabolic enzymes and the risk of dementia, as well as whether genetic factors can explain these potential associations, remains unclear.
Kaicheng Li   +12 more
doaj   +1 more source

Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity

open access: yes, 1978
Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases.
Kobayashi, Michio
core   +1 more source

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