Characterization of the human omega-oxidation pathway for omega-hydroxy-very-long-chain fatty acids [PDF]
Very-long-chain fatty acids (VLCFAs) have long been known to be degraded exclusively in peroxisomes via beta-oxidation. A defect in peroxisomal beta-oxidation results in elevated levels of VLCFAs and is associated with the most frequent inherited ...
Dacremont, Georges +4 more
core +2 more sources
Deciphering the role of liver metabolic enzymes in dementia pathogenesis
The relationship between liver metabolic enzymes and the risk of dementia, as well as whether genetic factors can explain these potential associations, remains unclear.
Kaicheng Li +12 more
doaj +1 more source
Intracellular proteolytic enzymes of liver [PDF]
The influence of reaction upon autolysis of animal tissues has been exhaustively studied. All observers agree upon the favorable influence of a weak acid medium, and upon the inhibitory effect alkaline reaction. As an example of the influence of reaction upon autolysis, 2.5 grams of liver after five days at 37 degrees yield the following equivalents of
openaire +2 more sources
Pattern of Serum Liver Enzymes in the Patients with Type 2 Diabetes Mellitus [PDF]
Background & Aims: The liver plays an important role in the regulation of glucose concentration and metabolism. Diabetic patients develop abnormalities in liver enzymes affecting the liver and its function.
Manila Makaju +7 more
doaj
Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]
Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO +7 more
core +2 more sources
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
The Hepatocellular Hypoxia Criteria:2’Nitroimidazole Effect on Hepatocyte Carbohydrate Metabolizing Enzymes [PDF]
Aim: to understand the 2’-nitroimidazole induced hypoxia and liver cell interaction, we proposed a “Hapatocellular Hypoxia Criteria”.
Rakesh Sharma
core +1 more source
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai +4 more
wiley +1 more source
Lafora Disease Masquerading as Hepatic Dysfunction [PDF]
Lafora disease is fatal intractable progressive myoclonic epilepsy. It is frequently characterized by epileptic seizures, difficulty walking, muscle spasms, and dementia in late childhood or adolescence.
Abdullah, Hafez Mohammad A. +6 more
core +1 more source
The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1. [PDF]
BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1 ...
A Tostmann +79 more
core +2 more sources

