Results 51 to 60 of about 1,826,226 (307)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 2023 Introduction Chronic-plaque psoriasis is a chronic inflammatory dermatological disease. Obesity comorbidities, including non-alcoholic fatty liver disease, are highly prevalent in patients with chronic-plaque psoriasis.
Ramy Salama Draz +2 more
core +1 more source
Hepatic Steatosis: Can herbs cure this?
International Journal of Endorsing Health Science Research, 2018 Background: Accumulation of fat in the liver is known as liver steatosis which occurs as a result of obesity. Ginsenoside is glycosylated saponins easily found in Asia, Egypt and China.
Rabia Rehan +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Risk factors for alcohol recidivism after liver transplantation [PDF]
, 2021 Go to Background: Alcoholic liver disease (ALD) has been increasing recently and the second most common indication for liver transplantation (LT) in Korea.
이재근 +8 more
core +1 more source
Scientific Reports, 2021 Obesity is a global health concern because of its increasing trend both in developed and developing countries. A limited number of studies have evaluated the association of liver enzymes with both general and abdominal obesity in the general population ...
Nurshad Ali +10 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The Effect of Curcumin on Functional and Structural Alterations of the Liver in Rats after MDMA Consumption [PDF]
Journal of Kerman University of Medical Sciences, 2019 Background: Nowadays, one of the problems of human beings is drug addiction, which causes individual, economic and social damages. One of the most commonly used substances in parties is ecstasy pills or 3, 4-methylenedioxymethamphetamine (MDMA).
Naser Khalaji +6 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Fatty liver syndrome in captive bustards: Clinical, pathological and epidemiological findings [PDF]
, 1997 Clinical, pathological, and epidemiological findings are presented on fatty liver syndrome mainly in houbara bustards (Chlamydotis undulata macqueenii), but also in some other bustard species.
Nicholls, P.K. +2 more
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