Results 41 to 50 of about 849,982 (299)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
The Effect of Curcumin on Functional and Structural Alterations of the Liver in Rats after MDMA Consumption [PDF]
Journal of Kerman University of Medical Sciences, 2019 Background: Nowadays, one of the problems of human beings is drug addiction, which causes individual, economic and social damages. One of the most commonly used substances in parties is ecstasy pills or 3, 4-methylenedioxymethamphetamine (MDMA).
Naser Khalaji +6 more
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2022 Abdul Moeed Department of Internal Medicine, Dow University of Health Sciences, Karachi, PakistanCorrespondence: Abdul Moeed, Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan, Tel +92 3061159372, Email abdulmoeed117 ...
Moeed A
doaj
Emerging role of the pentose phosphate pathway in hepatocellular carcinoma [PDF]
, 2017 In recent years, there has been a revival of interest in metabolic changes of cancer cells as it has been noticed that malignant transformation and metabolic reprogramming are closely intertwined.
Columbano, Amedeo +2 more
core +2 more sources
EXPERIMENTAL LIVER NECROSIS; II. ENZYMES [PDF]
Journal of Experimental Medicine, 1907 1. The presence of blood serum has a decided inhibitory effect on autolysis. Thus in the normal unwashed organs the non-coagulable nitrogen increase was 100 to 300 per cent., while in the washed it amounted to 450 per cent. The washed necrotic livers showed an increase of from 600 to 850 per cent., while that of the unwashed necrotic was only slightly ...
R M, Pearce, H C, Jackson
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Hepatic Steatosis: Can herbs cure this?
International Journal of Endorsing Health Science Research, 2018 Background: Accumulation of fat in the liver is known as liver steatosis which occurs as a result of obesity. Ginsenoside is glycosylated saponins easily found in Asia, Egypt and China.
Rabia Rehan +3 more
doaj +1 more source
Comparative study of the hypoglycemic and biochemical effects of Catharanthus roseus (Linn) g. apocynaceae (Madagascar periwinkle) and chlorpropamide (diabenese) on alloxan-induced diabetic rats [PDF]
, 2005 The effect of the aqueous extracts of Catharanthus roseus and chlorpropamide (Diabenese) on the levels of serum cholesterol, total protein, lipid peroxidation, blood glucose and liver enzymes were compared in alloxan-induced diabetic rats.
Iweala, E. E. J., Okeke, C. U.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source