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Apollo Medicine, 2021 Acute liver failure is an uncommon disease presenting with abrupt failure of liver synthetic and detoxification functions on account of widespread damage to hepatocytes and is associated with high mortality.
Vikash Prakash
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A Case of Metformin-Associated Lactic Acidosis Complicated by Acute Liver Failure, Acute Renal Failure, and Shock. [PDF]
CureusMetformin is an oral antihyperglycemic agent used for type 2 diabetes mellitus (T2DM) management and is considered to be the first-line treatment for diabetic patients.
Farouji A +4 more
europepmc +2 more sources
Procalcitonin Identifies Cell Injury, Not Bacterial Infection, in Acute Liver Failure. [PDF]
PLoS ONE, 2015 Because acute liver failure (ALF) patients share many clinical features with severe sepsis and septic shock, identifying bacterial infection clinically in ALF patients is challenging.
Jody A Rule +6 more
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Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure. [PDF]
PLoS ONE, 2015 Acute liver failure is a rare but catastrophic condition which can progress rapidly to multi-organ failure. Studies investigating the onset of individual organ injury such as the liver, kidneys and brain during the evolution of acute liver failure, are ...
Luisa A Baker +9 more
doaj +12 more sources
Annals of Hepatology, 2010 Acute liver failure is a rare but often catastrophic illness affecting the liver and multiple organ systems. Patients with acute liver failure require a multidisciplinary approach for adequate management.
Murali Pathikonda, Santiago J. Munoz, MD
doaj +5 more sources
Acute Liver Failure Guidelines
American Journal of Gastroenterology, 2023 Acute liver failure (ALF) is a rare, acute, potentially reversible condition resulting in severe liver impairment and rapid clinical deterioration in patients without preexisting liver disease. Due to the rarity of this condition, published studies are limited by the use of retrospective or prospective cohorts and lack of randomized controlled trials ...
Alexandra Shingina +7 more
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Hypothermia in Acute Liver Failure [PDF]
Metabolic Brain Disease, 2004 The development of encephalopathy in patients with acute liver injury defines the occurrence of liver failure. The encephalopathy of acute liver failure is characterized by brain edema which manifests clinically as increased intracranial pressure. Despite the best available medical therapies a significant proportion of patients with acute liver failure
Jalan, Rajiv, Rose, Christopher
openaire +5 more sources
Pediatric Reports, 2023 Pediatric acute liver failure (PALF) has recently become a subject of great interest when multiple clusters of non-A to non-E severe acute hepatitis in otherwise healthy young children with a median age of 2 years were reported around the world [...]
Claudia Mandato, Pietro Vajro
doaj +3 more sources
Journal of Pediatric Critical Care, 2019 Out of various etiology involved in liver pathology viral and metabolic causes are important in children. Hypoxic and ischemic liver injury are commonly seen in PICU.
Kundan Mittal +2 more
doaj +3 more sources
The Lancet, 2020 Acute liver failure is a rare syndrome and is primarily caused by paracetamol toxicity in developed nations. Survival for patients with acute liver failure has steadily improved over the last few decades from approximately 20% to greater than 60%. This marked improvement in survival has been due to a combination of improvements in medical practice and ...
Sandro, Vento, Francesca, Cainelli
+9 more sources