Results 1 to 10 of about 585,288 (267)
Procalcitonin Identifies Cell Injury, Not Bacterial Infection, in Acute Liver Failure. [PDF]
Because acute liver failure (ALF) patients share many clinical features with severe sepsis and septic shock, identifying bacterial infection clinically in ALF patients is challenging.
Jody A Rule+6 more
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Acute liver failure is an uncommon disease presenting with abrupt failure of liver synthetic and detoxification functions on account of widespread damage to hepatocytes and is associated with high mortality.
Vikash Prakash
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Acute liver failure is a rare but often catastrophic illness affecting the liver and multiple organ systems. Patients with acute liver failure require a multidisciplinary approach for adequate management.
Murali Pathikonda, Santiago J. Munoz, MD
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Pediatric acute liver failure (PALF) has recently become a subject of great interest when multiple clusters of non-A to non-E severe acute hepatitis in otherwise healthy young children with a median age of 2 years were reported around the world [...]
Claudia Mandato, Pietro Vajro
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Out of various etiology involved in liver pathology viral and metabolic causes are important in children. Hypoxic and ischemic liver injury are commonly seen in PICU.
Kundan Mittal+2 more
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Acute liver failure is a rare syndrome and is primarily caused by paracetamol toxicity in developed nations. Survival for patients with acute liver failure has steadily improved over the last few decades from approximately 20% to greater than 60%. This marked improvement in survival has been due to a combination of improvements in medical practice and ...
Sandro, Vento, Francesca, Cainelli
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Predicting outcome on admission and post-admission for acetaminophen-induced acute liver failure using classification and regression tree models. [PDF]
Assessing prognosis for acetaminophen-induced acute liver failure (APAP-ALF) patients often presents significant challenges. King's College (KCC) has been validated on hospital admission, but little has been published on later phases of illness. We aimed
Jaime Lynn Speiser+3 more
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Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure. [PDF]
Tools to predict death or spontaneous survival are necessary to inform liver transplantation (LTx) decisions in pediatric acute liver failure (PALF), but such tools are not available.
Nabil Azhar+6 more
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Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors. [PDF]
Acetaminophen (APAP) hepatotoxicity is related to the formation of N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified through conjugation with reduced glutathione (GSH).
Gurnit Kaur+6 more
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Acute liver failure in children is a rare but potentially fatal disease. Causes of ALF in neonatal period are different from those in early or late childhood. Despite the improvement in the paediatric intensive care, liver transplantation remains the only effective treatment.
Bansal, Sanjay, Dhawan, Anil
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