Results 101 to 110 of about 509,312 (356)
Epigenetics and Liver Fibrosis [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2017 Liver fibrosis arises because prolonged injury combined with excessive scar deposition within hepatic parenchyma arising from overactive wound healing response mediated by activated myofibroblasts. Fibrosis is the common end point for any type of chronic liver injury including alcoholic liver disease, nonalcoholic fatty liver disease, viral hepatitis ...Moran-Salvador E, Mann Jopenaire +3 more sourcesNano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Advanced Functional Materials, EarlyView.Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer +6 morewiley +1 more sourceIdentification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. [PDF]
, 2017 Fibrotic diseases contribute to 45% of deaths in the industrialized world, and therefore a better understanding of the pathophysiological mechanisms underlying tissue fibrosis is sorely needed.Amatucci, Aldo, Anderson, Daniel G, Brenner, David, Burkly, Linda C, Cameron, Thomas O, Cao, Lizhi, Dalkilic-Liddle, Isin, Duffield, Jeremy, Hamann, Stefan, Hossbach, Markus, Kauffman, Kevin J, Kisseleva, Tatiana, Koteliansky, Victor, Mir, Faryal F, Novobrantseva, Tatiana, Reynolds, Taylor, Vollmann, Elisabeth H +16 morecore +2 more sourcesDual‐Layer Living Hydrogel Enables On‐Demand Delivery of Phages and Probiotics for Synergistic Wound Infection Therapy
Advanced Functional Materials, EarlyView.A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.Siyuan Tao, Darine D'Adam, Anna Hu, Sixuan Zhang, Josua Roduner, Katharina Maniura‐Weber, Qun Ren +6 morewiley +1 more sourceCost-effectiveness of non-invasive methods for assessment and monitoring of liver fibrosis and cirrhosis in patients with chronic liver disease: systematic review and economic evaluation [PDF]
, 2015 BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis in chronic liver disease; however, it is invasive, with the potential for serious complications., , , , , , , , , , , , , , , , , , , , , , , Adams, Adams, Afdhal, Aguirre, Ahmad, Aithal, Al-Mohri, Anaparthy, Andersson, Angulo, Arena, Argo, Asbach, Ascher, Aube, Aube, Awaya, Barshop, Barton, Bataller, Beckebaum, Bedossa, Bejarano, Belfort, Bellentani, Ben Jazia, Bennett, Berg, Blomme, Bolondi, Bonkovsky, Boring, Borroni, Bourliere, Boursier, Boursier, Briggs, Brown, Brunetto, Buntinx, Burton, Cales, Cales, Cales, Calvaruso, Calvaruso, Calvaruso, Camma, Cardi, Cardoso, Carlson, Carrion, Carvalho-Filho, Castera, Castera, Castera, Castera, Castera, Castera, Ceriani, Chalasani, Chalasani, Chan, Chang, Chavez-Tapia, Cheinquer, Chen, Chen, Chen, Cheung, Cho, Cholongitas, Chong, Chou, Christensen, Chrysanthos, Cioni, Claxton, Cobbold, Colletta, Colli, Colli, Colombo, Corradi, Crespo, Cross, Crowley, Crowley, Curtis, da Silva, Dakin, Danila, David, Davis, de Franchis, De Freitas, De Jongh, de Ledinghen, De Ledinghen, Degos, Denzer, Detre, Di Bisceglie, Di Marco, Dinesen, Dixon, Dixon, Do, Donnan, Drummond, Dusheiko, D’Amico, D’Onofrio, Ekstedt, Esmat, Esteban, Fabris, Fahmy, Fattovich, Fattovich, Fattovich, Fattovich, Fattovich, Fattovich, Feldstein, Fenwick, Ferral, Fontaine, Fontana, Fontanges, Forestier, Forns, Fraquelli, Fried, Fried, Friedrich-Rust, Fujii, Fujimoto, Fung, Gaia, Gaia, Gaiani, Ganne-Carrie, Gara, Germani, Germani, Giannini, Gierblinski, Gobel, Goodman, Goyal, Grieve, Grishchenko, Guajardo-Salinas, Guechot, Guechot, Guha, Gui, Guo-Qiu, Guzelbulut, Hadziyannis, Halfon, Halfon, Halfon, Hall, Harada, Harrison, Haukeland, Hongbo, Hoofnagle, Hsieh, Hu, Huang, Hui, Huwart, Iacobellis, Ibrahim, Idilman, Imbert-Bismut, Imperiale, Isgro, Ishibashi, Islam, Iushchuk, Jacobson, Jacobson, Jacobson, Janssens, John-Baptiste, Jones, Jones, Joseph, Kalantari, Kamal, Kamphues, Kandemir, Kaneda, Kayadibi, Kelleher, Kelleher, Khan, Khosravi, Kilpe, Kim, Kim, Kim, Kim, Kim, Kim, Kim, Kim, Koda, Koizumi, Kwok, Lackner, Ladenheim, Ladero, Lai, Lampertico, Lau, Lavallard, Lavanchy, Lavine, Lawitz, Lee, Lee, Lee, Leroy, Leroy, Leroy, Lesmana, Levy, Lewin, Li, Liaw, Liaw, Lichtinghagen, Lieber, Lin, Liu, Liu, Liu, Liu, Liu, Liu, Loko, Longworth, Lupsor, Lupsor, Lupsor, Lutz, Lydatakis, Macaskill, Macias, Macias, Mahadeva, Mahady, Mahady, Mallet, Manns, Manns, Manousou, Manousou, Marcellin, Marcellin, Marcellin, Martinez, Martinez, McLernon, McPherson, McPherson, Melin, Miailhes, Mohamadnejad, Moreno-Otero, Morgan, Morikawa, Motosugi, Mueller, Mummadi, Murawaki, Musso, Myers, Myers, Nagata, Nahon, Naveau, Naveau, Nguyen-Khac, Nishiura, Nitta, Nojiri, Numminen, Nunes, Obara, Ogawa, Oliveira, Ong, Orlacchio, Orlacchio, Osakabe, O’Shea, Paggi, Pais, Palmeri, Papalavrentios, Parise, Park, Park, Park, Park, Park, Parkes, Patel, Patel, Pawitpok, Pereira, Petta, Pimentel, Pohl, Poordad, Poynard, Poynard, Poynard, Poynard, Prati, Promrat, Qian, Qiu, Qureshi, Raftopoulos, Rakoski, Ramachandran, Raszeja-Wyszomirska, Ratziu, Ratziu, Ratziu, Ratziua, Realdi, Reedy, Reitsma, Ronot, Rosenberg, Rossi, Rossini, Ruffillo, Rustogi, Saab, Said, Saitou, Sakugawa, Sancheztapias, Sandrasegaran, Santos, Sanvisens, Sanyal, Sanyal, Sanyal, Schiavon, Schiavon, Schneider, Schneider, Schuetz, Sebastian, Sebastiani, Sebastiani, Sebastiani, Sebastiani, Sene, Seto, Sharabash, Shastry, Shen, Shepherd, Shepherd, Shepherd, Sherman, Sheth, Shields, Shiffman, Shimada, Shin, Shinkins, Shiramizu, Siebert, Sinakos, Singal, Sirli, Snyder, Snyder, Sohn, Sohn, Sokucu, Sonnenberg, Sporea, Sporea, Sporea, Sporea, Sporea, Standish, Sterling, Stevenson, Stibbe, Sud, Sumida, Sumida, Suzuki, Sweeting, Takeda, Tassopoulos, Terjung, Testa, Thompson, Thompson, Thompson, Thompson Coon, Thompson Coon, Tillmann, Tome, Toniutto, Tran, Trang, Trifan, Trocme, Tsochatzis, Tsochatzis, Tsochatzis, Tsochatzis, Tsochatzis, Tural, Uygun, Vallet-Pichard, Valva, Vanbiervliet, Varaut, Veenstra, Veenstra, Venkatesh, Vernon, Verrill, Viana, Vigano, Viganò, Wai, Wang, Wang, Ware, Westin, Whiting, Whiting, Whiting, Whiting, Wilby, Wilck, Wilson, Wong, Wong, Wong, Wong, Wong, Wong, Wong, Wong, Woo, Wright, Wu, Xu, Yoneda, Yoneda, Younossi, Younossi, Yuen, Zaman, Zarski, Zarski, Zhang, Zhang, Zhang, Zhu, Zhu, Ziol +503 morecore +2 more sourcesArtificial Intelligence as the Next Visionary in Liquid Crystal Research
Advanced Functional Materials, EarlyView.The functions of AI in the research laboratory are becoming increasingly sophisticated, allowing the entire process of hypothesis formulation, material design, synthesis, experimental design, and reiterative testing to be automated. In our work, we conceive how the incorporation of AI in the laboratory environment will transform the role and ...Mert O. Astam, Ouassim L'Karkouri, Danqing Liu +2 morewiley +1 more sourcePrevalence of clinically significant liver fibrosis in the general population: A systematic review and meta-analysis [PDF]
Clinical and Molecular HepatologyBackground/Aims Although important, clinically significant liver fibrosis is often overlooked in the general population. We aimed to examine the prevalence of clinically significant liver fibrosis using noninvasive tests (NITs) in the general population. Hee Yeon Kim, Jung Hwan Yu, Young Eun Chon, Seung Up Kim, Mi Na Kim, Ji Won Han, Han Ah Lee, Young-Joo Jin, Jihyun An, Miyoung Choi, Dae Won Jun +10 moredoaj +1 more sourceHybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis [PDF]
, 2016 Liver fibrosis, a consequence of chronic liver injury and a way station to cirrhosis and hepatocellular carcinoma, lacks effective treatment. Endocannabinoids acting via cannabinoid-1 receptors (CB1R) induce profibrotic gene expression and promote ...Cao, Z., Cinar, R., Erdélyi, Katalin, Iyer, M. R., Jourdan, T., Liu, Z., Pacher, Pál, Szanda, Gergő +7 morecore +1 more sourceDecellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis
Advanced Healthcare Materials, EarlyView.Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan +13 morewiley +1 more sourceGaucher Disease and Myelofibrosis: A Combined Disease or a Misdiagnosis? [PDF]
, 2018 Background: Gaucher disease (GD) and primary myelofibrosis (PMF) share similar clinical and laboratory features, such as cytopenia, hepatosplenomegaly, and marrow fibrosis, often resulting in a misdiagnosis.Cardarelli, L, Foà, R, Giona, F, Mariani, S, Palumbo, G, Santopietro, M +5 morecore +1 more source