Results 211 to 220 of about 509,312 (356)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

The Role of Macrophage Polarization and Ferroptosis in the Progression of Liver Fibrosis. [PDF]

Can J Gastroenterol Hepatol
Purnama JN, Ghozali M, Malini DM, Safitri R.   +3 more
europepmc   +1 more source

Cytokines and Liver Fibrosis

Japanese Journal of Clinical Immunology, 2000
K, Kayano, E, Sakaguchi, I, Sakaida, K, Okita   +3 more
openaire   +3 more sources

Long term outcome of liver transplantation (LT) for patients with cystic fibrosis liver disease (CFLD)

, 2010
Indra van Mourik, J. K. Dowman, David Watson, J.L. Whitehouse, Christopher E. M. Lloyd, Bridget Gunson, D. Honeybourne, J. Buckels, D. Kelly, Philip N. Newsome   +9 more
openalex   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Deciphering the Role of Oroxylin A in Liver Fibrosis. [PDF]

Drug Des Devel Ther
Wang S, Wu J, Sun J, Chen W, Tian Z, Huang S, Wang M.   +6 more
europepmc   +1 more source

Scientometric Analysis of Publications on Liver Fibrosis & Nutrition Therapy: Mapping and Visualization

Hadis Gerami, Rasha Atlasi, Roya Naeimi
openalex   +1 more source

Tu1907 – Liver Fibrosis Stage At Baseline Predicts Outcome of Metabolic Surgery

, 2019
Christian Kienbacher, Maria Wakolbinger, Stefan Traussnigg, Renate Kruschitz, Tanja Wuerger, Karin Schindler, Arnulf Ferlitsch, Gerhard Prager, Bernhard Ludvik, Michael Trauner   +9 more
openalex   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Ferroptosis in liver fibrosis and its potential intervention strategy. [PDF]

Cell Biol Toxicol
Zhu W, Fu L, Cui Y, Tang Y, Liu K, Shi L, Gao Y, Li M, Huang L.   +8 more
europepmc   +1 more source