Results 241 to 250 of about 509,312 (356)

The classification of liver fibrosis stage for all experimental groups assessed by Metavir scoring system.

Natnicha Suttawong (22367172), Namthip Witayavanitkul (8919254), Maneerat Chayanupatkul (8919260), Natcha Wanpiyarat (12912166), Pornpen Werawatganone (22367175), Prasong Siriviriyakul (8919269), Duangporn Werawatganon (9223419)   +6 more
openalex   +1 more source

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

Circular RNA encoding relaxin-2 as a potential therapy for liver fibrosis. [PDF]

Mol Ther Nucleic Acids
Zhong J, Zhang Z, Xiao L, Wang C, Yang Y, Zhang Q, Wang Z.   +6 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Cell-specific roles of autophagy in liver fibrosis: implications for targeted pharmacotherapy. [PDF]

Ann Med
Liu C, Yang H, Liu Y, An M, Weng Z, Li L.   +5 more
europepmc   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

Association of estimated liver fibrosis with carotid but not femoral atherosclerotic burden: the ILERVAS cohort. [PDF]

Front Endocrinol (Lausanne)
León-Mengíbar J, Malagón MM, Bermúdez-López M, Valdivielso JM, Pamplona R, Torres G, Mauricio D, Castro E, Fernández E, Caixàs A, Hernández M, Lopez-Cano C, Gordon A, Guzman-Ruiz R, Cusi K, Lecube A.   +15 more
europepmc   +1 more source

Platelet C3G protects from liver fibrosis, while enhancing tumor growth through regulation of the immune response

Cristina Baquero, Minerva Iniesta‐González, Nerea Palao, Cristina Fernández‐Infante, Mateo Cueto‐Remacha, Jaime Mancebo, Samuel de la Cámara Fuentes, María Rodrigo‐Faus, M. Pilar Valdecantos, Ángela M. Valverde, Celia Sequera, Sara Manzano, Ángel M. Cuesta, Álvaro Gutiérrez-Uzquiza, Paloma Bragado, Carmen Guerrero, Almudena Porrás   +16 more
openalex   +2 more sources

Evaluation of ballooned hepatocytes as a risk factor for future progression of fibrosis in patients with non-alcoholic fatty liver disease

, 2018
Keisuke Kakisaka, Yuji Suzuki, Yudai Fujiwara, Tamami Abe, Miki Yonezawa, Hidekatsu Kuroda, Kazuyuki Ishida, Tamotsu Sugai, Yasuhiro Takikawa   +8 more
openalex   +2 more sources

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source