Results 21 to 30 of about 1,327,541 (308)

The Determinants of Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus

Biomedicines, 2022
Liver fibrosis is a key pathophysiology process in chronic liver disease. It is still unclear whether the impact of liver fibrosis is not fully realized in type 2 diabetes mellitus (T2D) patients with nonalcoholic fatty liver disease (NAFLD), and the ...
Chia-Yen Dai, Tzu-Jung Fang, Wei-Wen Hung, Hui-Ju Tsai, Yi-Chun Tsai   +4 more
doaj   +1 more source

Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis [PDF]

, 2010
Background: FibroTest (FT) is the most frequently used serum fibrosis marker and consists of an algorithm of five fibrosis markers (alfa2-macroglobulin, apolipoproteinA1, haptoglobin, GGT, bilirubin). The Enhanced Liver Fibrosis (ELF) test consists of an
Julie Parkes, Stefan Zeuzem, Herrmann, Eva, Friedrich-Rust, Mireen, William Rosenberg, Sarrazin, Christopher, Mireen Friedrich-Rust, Sarrazin, Christoph, Christoph Sarrazin, Parkes, Julie, Eva Herrmann, Rosenberg, William, Zeuzem, Stefan   +12 more
core   +2 more sources

Combi-Elasto Evaluation of the Degree of Liver Fibrosis in Children with Cholestatic Liver Disease

Diagnostics, 2023
Cholestatic liver disease is a common liver disease in infants and young children. Liver fibrosis is a key factor affecting the prognosis, and liver transplantation is the only treatment option for liver cirrhosis.
Rina Li, Caihui Hu, Fenglin Xu, Qi Zhang, Fazhi Zhou, Chenpeng Zheng, Yang Gao, Yi Tang, Jingyu Chen   +8 more
doaj   +1 more source

Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers [PDF]

, 2012
Background: Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly attributable to co-infection with hepatitis B or C. The impact of other risk factors, including prolonged exposure to combined antiretroviral therapy (cART ...
Annika Vermehren, Stefan Zeuzem, Gute, Peter, Poynard, Thierry, Friedrich-Rust, Mireen, Vermehren, Johannes, Peter Gute, Sarrazin, Christoph, Christoph Sarrazin, Amina Carlebach, Johannes Vermehren, Carlebach, Amina, Axel Mueller, Vermehren, Annika, Lutz, Thomas, Forestier, Nicole, Herrmann, Eva, Thomas Lutz, Thierry Poynard, Mireen Friedrich-Rust, Knecht, Gaby, Wolf Peter Hofmann, Hofmann, Wolf-Peter, Eva Herrmann, Nicole Forestier, Gaby Knecht, Mueller, Axel, Zeuzem, Stefan   +27 more
core   +2 more sources

Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease. [PDF]

, 2013
Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify new experimental biomarkers for the detection of CFLD.
Richard Schulz, Martin Roderfeld, Roderfeld, Martin, Lisa Hage, Timo Rath (389419), Reinhart Zachoval (76840), Katrin Menendez Menendez (389422), Lutz Naehrlich (389423), Martin Roderfeld (389425), Hage, Lisa, Marion Kügler, Richard Schulz (389424), Marion Kügler (389421), Elke Roeb (389426), Timo Rath, Kügler, Marion, Rath, Timo, Roeb, Elke, Katrin Menendez Menendez, Reinhart Zachoval, Elke Roeb, Menendez Menendez, Katrin, Lutz Naehrlich, Lisa Hage (389420), Zachoval, Reinhart, Naehrlich, Lutz, Schulz, Richard   +26 more
core   +1 more source

Association between Sarcopenic Obesity Status and Nonalcoholic Fatty Liver Disease and Fibrosis [PDF]

, 2023
Background/aims: There are no data regarding the association between sarcopenic obesity status and nonalcoholic fatty liver disease (NAFLD) and NAFLD-associated liver fibrosis.
박종숙, 이현웅, 백수정, 유성환, 이병권   +4 more
core   +1 more source

Cirrhotic Human Liver Extracellular Matrix 3D Scaffolds Promote Smad-Dependent TGF-β1 Epithelial Mesenchymal Transition

Cells, 2019
An altered liver microenvironment characterized by a dysregulated extracellular matrix (ECM) supports the development and progression of hepatocellular carcinoma (HCC). The development of experimental platforms able to reproduce these physio-pathological
Giuseppe Mazza, Andrea Telese, Walid Al-Akkad, Luca Frenguelli, Ana Levi, Martina Marrali, Lisa Longato, Kessarin Thanapirom, Maria Giovanna Vilia, Benedetta Lombardi, Claire Crowley, Mark Crawford, Morten A. Karsdal, Diana J. Leeming, Giusi Marrone, Katrin Bottcher, Benjamin Robinson, Armando Del Rio Hernandez, Domenico Tamburrino, Gabriele Spoletini, Massimo Malago, Andrew R. Hall, Jasminka Godovac-Zimmermann, Tu Vinh Luong, Paolo De Coppi, Massimo Pinzani, Krista Rombouts   +26 more
doaj   +1 more source

Diagnostic Accuracy of Indocyanine Green Clearance Test for Different Stages of Liver Fibrosis and Cirrhosis

Diagnostics, 2023
(1) Background: This study aimed to correlate the indocyanine green clearance (ICG) test with histopathological grades of liver fibrosis and liver cirrhosis to assess its diagnostic accuracy in differentiating normal liver parenchyma from liver fibrosis ...
Lukas Luerken, Marco Dollinger, Andrea Goetz, Kirstin Utpatel, Michael Christian Doppler, Jakob Benedikt Weiss, Wibke Uller, André Ignee, Niklas Verloh, Michael Haimerl   +9 more
doaj   +1 more source

Reversal of liver fibrosis

Saudi Journal of Gastroenterology, 2009
Hepatic fibrosis is a scarring process associated with an increased and altered deposition of extracellular matrix in the liver. It is caused by a variety of stimuli and if fibrosis continues unopposed, it would progress to cirrhosis which poses a significant health problem worldwide.
Ismail Mona, Pinzani Massimo
openaire   +3 more sources

GDF15 Ameliorates Liver Fibrosis by Metabolic Reprogramming of Macrophages to Acquire Anti-Inflammatory PropertiesSummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Liver fibrosis/cirrhosis is significant health burden worldwide, resulting in liver failure or cancer and accounting for many deaths each year.
Xiaolei Li, Qian Huai, Cheng Zhu, Xu Zhang, Wentao Xu, Hanren Dai, Hua Wang   +6 more
doaj   +1 more source