Results 31 to 40 of about 1,327,541 (308)
Reversibility of liver fibrosis [PDF]
Fibrogenesis & Tissue Repair, 2012 Liver fibrosis, and its end stage cirrhosis are a major cause of morbidity and mortality and therapeutic options are limited. However, the traditional view of liver disease as an irreversible process is obsolete and it is now evident that the development of liver fibrosis is a dynamic and potentially bidirectional process.
Pellicoro, Antonella +2 more
openaire +3 more sources
BMC Medical Imaging, 2021 Background To evaluate different stages of liver fibrosis in cynomolgus monkeys by comparing magnetic resonance-perfusion weighted imaging (MR-PWI) quantitative and semi-quantitative parameters, and confirm the best detection indicators for diagnosis of ...
Ke Ding +7 more
doaj +1 more source
Endoglin in liver fibrosis [PDF]
Journal of Cell Communication and Signaling, 2011 Liver fibrosis occurs in most types of chronic liver diseases and is characterized by excessive accumulation of extracellular matrix proteins, leading to disruption of tissue function and eventually organ failure. Transforming growth factor (TGF)-β represents an important pro-fibrogenic factor and aberrant TGF-β action has been implicated in many ...
Kenneth W, Finnson, Anie, Philip
openaire +2 more sources
Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B [PDF]
, 2005 Background: HBV infection is a serious global heath problem. It is crucial to monitor this disease more closely with a non-invasive marker in clinical trials.
Montazeri, G. +30 more
core +2 more sources
Journal of Diabetes Investigation, 2022 Aims/Introduction To investigate whether the Fibrosis‐4 index can help stratify the risk of diabetes mellitus in patients with fatty liver disease.
Yasuhiko Todo +19 more
doaj +1 more source
The role of hepatic microenvironment in hepatic fibrosis development
Annals of Medicine, 2022 Aim Fibrosis is a common pathological feature of most types of chronic liver injuries. There is no specific treatment for liver fibrosis at present. The liver microenvironment, which fosters the survival and activity of liver cells, plays an important ...
Ying Meng +3 more
doaj +1 more source
Hypoxia-induced factor and its role in liver fibrosis [PDF]
PeerJ, 2022 Liver fibrosis develops as a result of severe liver damage and is considered a major clinical concern throughout the world. Many factors are crucial for liver fibrosis progression.
Jan Mohammad Omar, Yang Hai, Shizhu Jin
doaj +2 more sources
Hyaluronic acid levels predict risk of hepatic encephalopathy and liver-related death in HIV/viral hepatitis coinfected patients [PDF]
, 2013 Background: Whereas it is well established that various soluble biomarkers can predict level of liver fibrosis, their ability to predict liver-related clinical outcomes is less clearly established, in particular among HIV/viral hepatitis co-infected ...
Soriano, V +38 more
core +3 more sources
Reversibility of liver fibrosis [PDF]
Clinics and Research in Hepatology and Gastroenterology, 2015 Liver fibrosis is a serious health problem worldwide, which can be induced by a wide spectrum of chronic liver injuries. However, until today, there is no effective therapy available for liver fibrosis except the removal of underlying etiology or liver transplantation. Recent studies indicate that liver fibrosis is reversible when the causative agent(s)
Mengxi Sun, Tatiana Kisseleva
openaire +2 more sources
MicroRNAs in fibrosis: opportunities and challenges [PDF]
, 2016 MicroRNAs (miRNAs) are small, non-coding RNAs that mediate mRNA cleavage, translational repression or mRNA destabilisation and are around 22-25 nucleotides in length via partial complementary binding to the 3' untranslated region in target transcripts ...
O'Reilly, Steven, Steven O’Reilly
core +1 more source