Results 31 to 40 of about 490,020 (307)
BMC Medical Imaging, 2021 Background To evaluate different stages of liver fibrosis in cynomolgus monkeys by comparing magnetic resonance-perfusion weighted imaging (MR-PWI) quantitative and semi-quantitative parameters, and confirm the best detection indicators for diagnosis of ...
Ke Ding +7 more
doaj +1 more source
The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. [PDF]
, 2017 Cytochrome P450 2E1 (CYP2E1) plays an important role in alcohol and toxin metabolism by catalyzing the conversion of substrates into more polar metabolites and producing reactive oxygen species.
Brenner, David A +11 more
core +1 more source
Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. [PDF]
, 2017 BackgroundReliable non-invasive markers to characterize inflammation, hepatocellular ballooning, and fibrosis in nonalcoholic fatty liver disease (NAFLD) are lacking.
Ann Scheimann +14 more
core +1 more source
Saudi Journal of Gastroenterology, 2009 Hepatic fibrosis is a scarring process associated with an increased and altered deposition of extracellular matrix in the liver. It is caused by a variety of stimuli and if fibrosis continues unopposed, it would progress to cirrhosis which poses a significant health problem worldwide.
Ismail Mona, Pinzani Massimo
openaire +3 more sources
Increased prevalence of advanced liver fibrosis in patients with psoriasis: A cross-sectional analysis from the rotterdam study [PDF]
, 2016 Prevalence of non-alcoholic fatty liver disease is increased in patients with psoriasis. However, it is not known how liver fibrosis correlates with psoriasis.
Hofman, A. (Albert) +7 more
core +1 more source
Reversibility of liver fibrosis [PDF]
Clinics and Research in Hepatology and Gastroenterology, 2015 Liver fibrosis is a serious health problem worldwide, which can be induced by a wide spectrum of chronic liver injuries. However, until today, there is no effective therapy available for liver fibrosis except the removal of underlying etiology or liver transplantation. Recent studies indicate that liver fibrosis is reversible when the causative agent(s)
Mengxi Sun, Tatiana Kisseleva
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The roles and mechanisms of hypoxia in liver fibrosis
Journal of Translational Medicine, 2021 Liver fibrosis occurs in response to any etiology of chronic liver injury. Lack of appropriate clinical intervention will lead to liver cirrhosis or hepatocellular carcinoma (HCC), seriously affecting the quality of life of patients, but the current ...
Jingyao Cai +3 more
doaj +1 more source
Timing for treatment of HCV recurrence after liver transplantation: the earlier the better. [PDF]
, 2016 HCV is the leading cause of death from liver disease and is the most common indication for a liver transplantation. Although HCV is a widespread health problem, disease management is particularly challenging in several key subpopulations, including liver
Burra, Patrizia +2 more
core +1 more source
Liver Fibrosis: Therapeutic Targets and Advances in Drug Therapy
Frontiers in Cell and Developmental Biology, 2021 Liver fibrosis is an abnormal wound repair response caused by a variety of chronic liver injuries, which is characterized by over-deposition of diffuse extracellular matrix (ECM) and anomalous hyperplasia of connective tissue, and it may further develop ...
Zui Tan +7 more
doaj +1 more source
Current Pathobiology Reports, 2015 Hepatocyte death, inflammation, and liver fibrosis are the hallmarks of chronic liver disease. Tumor necrosis factor-α (TNFα) is an inflammatory cytokine involved in liver inflammation and sustained liver inflammation leads to liver fibrosis. TNFα exerts inflammation, proliferation, and apoptosis.
Yang, Yoon Mee, Seki, Ekihiro
openaire +4 more sources