Results 11 to 20 of about 864,474 (360)

Metabolic Profile of C-Prenyl Coumarins Using Mass Spectrometry-Based Metabolomics

open access: yesMolecules, 2021
C-prenyl coumarins (C-PYCs) are compounds with similar structures and various bioactivities, which are widely distributed in medicinal plants. Until now, the metabolic characterizations of C-PYCs and the relationship between metabolism and bioactivities ...
Yan Cheng   +5 more
doaj   +1 more source

Proteomic analysis of small extracellular vesicles from the plasma of patients with hepatocellular carcinoma

open access: yesWorld Journal of Surgical Oncology, 2022
Purpose Liver cancer is one of the most common tumors with the seventh-highest incidence and the third-highest mortality. Many studies have shown that small extracellular vesicles (sEVs) play an important role in liver cancer.
Wei Dong   +9 more
doaj   +1 more source

Filter Drug-induced Liver Injury Literature with Natural Language Processing and Ensemble Learning [PDF]

open access: yes, 2022
Drug-induced liver injury (DILI) describes the adverse effects of drugs that damage liver. Life-threatening results including liver failure or death were also reported in severe DILI cases. Therefore, DILI-related events are strictly monitored for all approved drugs and the liver toxicity became important assessments for new drug candidates. These DILI-
arxiv   +1 more source

The contact system in liver injury [PDF]

open access: yesSeminars in Immunopathology, 2021
AbstractCoagulation is controlled by a delicate balance of prothrombotic and antithrombotic mechanisms, to prevent both excessive blood loss from injured vessels and pathologic thrombosis. The liver plays a pivotal role in hemostasis through the synthesis of plasma coagulation factors and their inhibitors that, in addition to thrombosis and hemostasis,
Chandini Rangaswamy   +4 more
openaire   +3 more sources

Longitudinal predictors of weapon involvement in middle adolescence: Evidence from the UK Millennium Cohort Study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 5-14, January 2023., 2023
Abstract This study uses longitudinal data from the UK Millennium Cohort Study (N = 13,277) to examine the childhood and early adolescence factors that predict weapon involvement in middle adolescence, which in this study is exemplified by having carried or used a weapon.
Aase Villadsen, Emla Fitzsimons
wiley   +1 more source

Tests of Liver Injury [PDF]

open access: yesClinical Medicine & Research, 2004
Liver test abnormalities are commonly found in ambulatory patients now that these tests are routinely included in chemistry panels. The majority of asymptomatic patients with liver test abnormalities have no evidence of liver disease. Recognizing the different patterns of liver injury can be used as a guide to direct further evaluation of diseases that
Ahmad S. Abdulkarim   +2 more
openaire   +3 more sources

Spillover and crossover effects of exposure to work‐related aggression and adversities: A dyadic diary study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 85-95, January 2023., 2023
Abstract The past two decades have produced extensive evidence on the manifold and severe outcomes for victims of aggression exposure in the workplace. However, due to the dominating individual‐centered approach, most findings miss a social network perspective.
Alexander Herrmann   +2 more
wiley   +1 more source

COMP Report: CPQR technical quality control guidelines for use of positron emission tomography/computed tomography in radiation treatment planning

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Positron emission tomography with x‐ray computed tomography (PET/CT) is increasingly being utilized for radiation treatment planning (RTP). Accurate delivery of RT therefore depends on quality PET/CT data. This study covers quality control (QC) procedures required for PET/CT for diagnostic imaging and incremental QC required for RTP.
Ran Klein   +7 more
wiley   +1 more source

Association of TM6SF2 rs58542926 T/C gene polymorphism with hepatocellular carcinoma: a meta-analysis

open access: yesBMC Cancer, 2019
Background Hepatocellular carcinoma (HCC) is the sixth-most common malignancy worldwide. Multiple previous studies have assessed the relationship between TM6SF2 gene polymorphism and the risk of developing HCC, with discrepant conclusions reached.
Shan Tang   +13 more
doaj   +1 more source

Drug Hepatotoxicity: Environmental Factors [PDF]

open access: yes, 2017
Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents.
Chalasani, Naga P., Stine, Jonathan G.
core   +1 more source

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