Results 11 to 20 of about 945,580 (358)
The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury [PDF]
, 2012 Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver dysfunction and the role of ...
Granja, Tiago +7 more
core +15 more sources
Vessels that encapsulate tumour clusters vascular pattern in hepatocellular carcinomaKey points
JHEP Reports, 2023 Summary: Vessels that encapsulate tumour clusters (VETC) is a distinct histologic vascular pattern associated with a novel mechanism of metastasis. First described in human cancers in 2004, its prevalence and prognostic significance in hepatocellular ...
Ken Liu +7 more
doaj +1 more source
The contact system in liver injury [PDF]
Seminars in Immunopathology, 2021 AbstractCoagulation is controlled by a delicate balance of prothrombotic and antithrombotic mechanisms, to prevent both excessive blood loss from injured vessels and pathologic thrombosis. The liver plays a pivotal role in hemostasis through the synthesis of plasma coagulation factors and their inhibitors that, in addition to thrombosis and hemostasis,
Chandini Rangaswamy +4 more
openaire +3 more sources
BMC Cancer, 2019 Background Hepatocellular carcinoma (HCC) is the sixth-most common malignancy worldwide. Multiple previous studies have assessed the relationship between TM6SF2 gene polymorphism and the risk of developing HCC, with discrepant conclusions reached.
Shan Tang +13 more
doaj +1 more source
Clinical Medicine & Research, 2004 Liver test abnormalities are commonly found in ambulatory patients now that these tests are routinely included in chemistry panels. The majority of asymptomatic patients with liver test abnormalities have no evidence of liver disease. Recognizing the different patterns of liver injury can be used as a guide to direct further evaluation of diseases that
Ahmad S. Abdulkarim +2 more
openaire +3 more sources
Epidemiology of Liver Injuries [PDF]
Scandinavian Journal of Surgery, 2003 Background and Aims: The aim of this study was to investigate the epidemiology of liver injuries and to grade injuries according to the Organ Injury Scale in a population-based study in Stockholm County comprising 1.75 million inhabitants. Material and Methods: Cases were retrieved from the National Board of Forensic Medicine and Public Health and ...
L. Iselius +3 more
openaire +3 more sources
A novel technique for selective NF-kappa B inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion. [PDF]
, 2009 Background and aims: The transcription factor nuclear factor kappa B (NF-kB) has risen as a promising target for anti-inflammatory therapeutics. In the liver, however, NFkB inhibition mediates both damaging and protective effects.
A. Hartkorn +11 more
core +1 more source
Red blood cell distribution width: a determinant of hospital mortality in pancreatitis [PDF]
Journal of Emergency Practice and Trauma, 2018 Objective: In recent years, there has been a great attention concerning red blood cell distribution width (RDW) in clinical decisions as well as determining the severity of diseases.
Payman Moharamzadeh +5 more
doaj +1 more source
Drug-induced liver injury [PDF]
Canadian Medical Association Journal, 2021 Drug-induced liver injury is estimated to have an incidence of 14–19 cases per 100 000 individuals.[1][1],[2][2] Although asymptomatic liver enzyme elevation is the most common presentation, drug-induced liver injury is the most common cause of acute liver failure in most Western countries,
Peter E. Wu, Alexander Kumachev
openaire +2 more sources
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
, 2002 Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A. +5 more
core +1 more source