Results 21 to 30 of about 452,276 (305)

Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study [PDF]

open access: yes, 2017
Background Radix Bupleuri (RB) has been popularly used for treating many liver diseases such as chronic hepatic inflammation and viral Hepatitis in China.
Huang, Youyi   +7 more
core   +2 more sources

Hypoxic Liver Injury [PDF]

open access: yesMayo Clinic Proceedings, 2006
Hypoxic liver injury is defined as a massive, but transient, increase in serum transaminase levels due to an imbalance between hepatic oxygen supply and demand in the absence of other acute causes of liver damage. It typically occurs in elderly individuals with right-sided congestive heart failure and low cardiac output.
openaire   +2 more sources

Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]

open access: yes, 2003
Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L   +4 more
core   +1 more source

Poly(γ-glutamic acid)-coated lipoplexes loaded with Doxorubicin for enhancing the antitumor activity against liver tumors

open access: yesNanoscale Research Letters, 2017
The study was to develop poly-γ-glutamic acid (γ-PGA)-coated Doxorubicin (Dox) lipoplexes that enhance the antitumor activity against liver tumors. γ-PGA-coated lipoplexes were performed by electrostatistically attracting to the surface of cationic ...
Na Qi, Bo Tang, Guang Liu, Xingsi Liang
doaj   +1 more source

MiR-26a-5p regulates proliferation, apoptosis, migration and invasion via inhibiting hydroxysteroid dehydrogenase like-2 in cervical cancer cell

open access: yesBMC Cancer, 2022
Background Evidences have indicated that miR-26a-5p regulates the malignant properties of various tumor cells. However, the influences of miR-26a-5p on proliferation, apoptosis and invasion are still vague in the cervical cancer (CC) cells.
Ming Li   +7 more
doaj   +1 more source

Endocannabinoid receptor blockade increases hepatocyte growth factor and reduces insulin levels in obese women with polycystic ovary syndrome [PDF]

open access: yes, 2016
There is evidence from animal and in-vitro studies that activation of the endocannabinoid system (EC) through cannabinoid receptor 1 (CB-1) is associated with liver injury, inflammation and hepatocellular carcinoma.1 Data suggests endogenous cannabinoids
Ahmed, Lina   +6 more
core   +1 more source

Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]

open access: yes, 2020
In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco   +4 more
core   +1 more source

MIF contributes to Trypanosoma brucei associated immunopathogenicity development [PDF]

open access: yes, 2014
African trypanosomiasis is a chronic debilitating disease affecting the health and economic well-being of many people in developing countries. The pathogenicity associated with this disease involves a persistent inflammatory response, whereby M1-type ...
Beschin, Alain   +11 more
core   +4 more sources

Can Viral Load Predict Liver Histology in Patients With Chronic Hepatitis B? [PDF]

open access: yesInternational Journal of Travel Medicine and Global Health, 2015
Introduction: Hepatitis B virus (HBV) infection is a global public health problem. Serum HBV DNA measurement is a non-invasive test that predicts the liver disease progression.
Ashraf Karbasi   +3 more
doaj   +1 more source

Mechanisms of isoniazid and rifampicin-induced liver injury and the effects of natural medicinal ingredients: A review

open access: yesFrontiers in Pharmacology, 2022
Isoniazid (INH) and rifampicin (RFP) are the first-line medications for tuberculosis treatment, and liver injury is the major adverse effect. Natural medicinal ingredients provide distinct benefits in alleviating patients’ symptoms, lowering the liver ...
Xiuping Zhuang   +7 more
doaj   +1 more source

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