Anti-tumor necrosis factor-alpha therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. [PDF]
, 2003 Klebsiella pneumoniae is a leading cause of gram-negative bacterial pneumonia, often resulting in bacteremia concurrent with the localized pulmonary infection.
Cogen, Anna L +4 more
core +1 more source
M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes. [PDF]
, 2017 Acute injury in the setting of liver fibrosis is an interesting and still unsettled issue. Most recently, several prominent studies have indicated the favourable effects of liver fibrosis against acute insults.
Bai, Li +13 more
core +2 more sources
Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases [PDF]
, 2020 In the past ten years, our understanding of the importance of bile acids has expanded from fat absorption and glucose/lipid/energy homeostasis into potential therapeutic targets for amelioration of chronic cholestatic liver diseases.
Alpini, Gianfranco +4 more
core +1 more source
Can Viral Load Predict Liver Histology in Patients With Chronic Hepatitis B? [PDF]
International Journal of Travel Medicine and Global Health, 2015 Introduction: Hepatitis B virus (HBV) infection is a global public health problem. Serum HBV DNA measurement is a non-invasive test that predicts the liver disease progression.
Ashraf Karbasi +3 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Isoniazid (INH) and rifampicin (RFP) are the first-line medications for tuberculosis treatment, and liver injury is the major adverse effect. Natural medicinal ingredients provide distinct benefits in alleviating patients’ symptoms, lowering the liver ...
Xiuping Zhuang +7 more
doaj +1 more source
Animal Models of Alcoholic Liver Disease for Hepatoprotective Activity Evaluation [PDF]
BIO Web of Conferences, 2021 Background: The reported statistics suggest that alcoholic liver disease is on the rise. Furthermore, medications used to treat the disease have unpleasant effects, and this necessitates the need to continuously investigate hepatoprotective agents.
Renggani Hidayah Dwi +2 more
doaj +1 more source
Drug-induced liver injury [PDF]
Nature Reviews Disease Primers, 2019 Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use. Drugs can be harmful to the liver in susceptible individuals owing to genetic and environmental risk ...
Neil Kaplowitz +13 more
openaire +5 more sources
Endocannabinoid receptor blockade increases hepatocyte growth factor and reduces insulin levels in obese women with polycystic ovary syndrome [PDF]
, 2016 There is evidence from animal and in-vitro studies that activation of the endocannabinoid system (EC) through cannabinoid receptor 1 (CB-1) is associated with liver injury, inflammation and hepatocellular carcinoma.1 Data suggests endogenous cannabinoids
Ahmed, Lina +6 more
core +1 more source
Mechanism and suggestions of liver damage caused by influenza A virus: a narrative review [PDF]
Infectious Diseases and Tropical MedicineThis study aimed to explore the causes and mechanisms of liver damage caused by influenza A virus (IAV), compare the liver damage caused by SARS-CoV-2 and IAV under China’s Glasnost, propose treatment and vaccination recommendations for IAV, and provide ...
Y. Yin, R. Luo, S. Li, R. Li
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundVessels that encapsulate tumor clusters (VETC) is a novel vascular pattern seen on hepatocellular carcinoma (HCC) histology which has been shown to independently predict tumor recurrence and survival after liver resection.
Claude Dennis +22 more
doaj +1 more source