Results 31 to 40 of about 4,185,241 (381)

Clinical characteristics of non‐ICU hospitalized patients with coronavirus disease 2019 and liver injury: A retrospective study

open access: yesLiver international (Print), 2020
Coronavirus disease 2019 (COVID‐19) has raised world concern for global epidemic since December, 2019. Limited data are available for liver function in COVID‐19 patients.
Hansheng Xie   +5 more
semanticscholar   +1 more source

A novel technique for selective NF-kappa B inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion. [PDF]

open access: yes, 2009
Background and aims: The transcription factor nuclear factor kappa B (NF-kB) has risen as a promising target for anti-inflammatory therapeutics. In the liver, however, NFkB inhibition mediates both damaging and protective effects.
A. Hartkorn   +11 more
core   +1 more source

Enoxaparin-Induced Liver Injury [PDF]

open access: yesCase Reports in Gastroenterology, 2020
Enoxaparin, a form of low-molecular-weight heparin, can cause a rare, underreported, and often reversible form of hepatocellular injury. This report describes a case of enoxaparin-induced hepatotoxicity in a 61-year-old male diagnosed with pulmonary embolism.
Patel Harish   +4 more
openaire   +4 more sources

Drug-induced liver injury [PDF]

open access: yesCanadian Medical Association Journal, 2021
Drug-induced liver injury is estimated to have an incidence of 14–19 cases per 100 000 individuals.[1][1],[2][2] Although asymptomatic liver enzyme elevation is the most common presentation, drug-induced liver injury is the most common cause of acute liver failure in most Western countries,
Peter E. Wu, Alexander Kumachev
openaire   +2 more sources

Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice

open access: yesNature Communications, 2023
Parabacteroides distasonis (P. distasonis), part of the gut microbiome, was reported to play a role in diabetes, colorectal cancer and inflammatory bowel disease. Here the authors report that P.
Qi Zhao   +12 more
doaj   +1 more source

Characteristics and Mechanism of Liver Injury in 2019 Coronavirus Disease

open access: yesJournal of Clinical and Translational Hepatology, 2020
An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (2019 coronavirus disease, COVID-19) since December 2019, from Wuhan, China, has been posing a significant threat to global human health.
Jie Li, Jian-Gao Fan
semanticscholar   +1 more source

Defining the temporal evolution of gut dysbiosis and inflammatory responses leading to hepatocellular carcinoma in Mdr2 −/− mouse model

open access: yesBMC Microbiology, 2021
Background Emerging evidence implicates the gut microbiome in liver inflammation and hepatocellular carcinoma (HCC) development. We aimed to characterize the temporal evolution of gut dysbiosis, in relation to the phenotype of systemic and hepatic ...
J. Behary   +14 more
doaj   +1 more source

Liver injury in COVID-19: The current evidence

open access: yesUnited European Gastroenterology journal, 2020
Patients with novel coronavirus disease 2019 (COVID-19) experience various degrees of liver function abnormalities. Liver injury requires extensive work-up and continuous surveillance and can be multifactorial and heterogeneous in nature.
S. Alqahtani, J. Schattenberg
semanticscholar   +1 more source

Saikosaponins induced hepatotoxicity in mice via lipid metabolism dysregulation and oxidative stress: a proteomic study [PDF]

open access: yes, 2017
Background Radix Bupleuri (RB) has been popularly used for treating many liver diseases such as chronic hepatic inflammation and viral Hepatitis in China.
Huang, Youyi   +7 more
core   +2 more sources

Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]

open access: yes, 2002
Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A.   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy