Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Author Correction: A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy [PDF]
, 2023 Liheng Che +16 more
openalex +1 more source
Osteopontin and `Melanoma Inhibitory Activity': Comparison of Two Serological Tumor Markers in Metastatic Uveal Melanoma Patients [PDF]
, 2009 Background: Evaluation of the protein osteopontin (OPN) as a potential new marker in comparison to melanoma inhibitory activity (MIA) for screening and detection of metastatic uveal melanoma. Methods: Plasma levels of 32 patients with uveal melanoma were
Haritoglou, Christos +5 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Platelet Volume Is Reduced In Metastasing Breast Cancer: Blood Profiles Reveal Significant Shifts
Cancer Management and Research, 2019 Ming-ming Li,1,* Chen-xi Yue,1,* Shuang Fu,1 Xin Zhang,1 Chang-Jiu Zhao,2 Rui-tao Wang1 1Department of Internal Medicine, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang 150081, People’s Republic of China;
Li M +5 more
doaj
Deep learning CT reconstruction improves liver metastases detection
Insights into ImagingObjectives Detection of liver metastases is crucial for guiding oncological management. Computed tomography through iterative reconstructions is widely used in this indication but has certain limitations.
Achraf Kanan +7 more
doaj +1 more source
Use of cytoceratin-20 in revealing of colorectal cancer metastases in liver [PDF]
Саратовский научно-медицинский журнал, 2013 The aim of the study is to evaluate the possibilities of immunohistochemical revealing of colorectal cancer micro-metastases in liver and to determine their prognostic significance. Material et metods.
Fedorina Т.A. +2 more
doaj
Liver metastases in patients with curatively treated colorectal cancer
Сибирский онкологический журнал, 2019 Background. The problem of the development of liver metastases in colorectal cancer patients previously treated with curative intent surgery remains little studied. Identification of significant factors affecting the occurrence of metachronous metastasis
R. I. Rasulov +2 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Clinical and molecular characterization of HER2 amplified-pancreatic cancer [PDF]
, 2013 <p>Background: Pancreatic cancer is one of the most lethal and molecularly diverse malignancies. Repurposing of therapeutics that target specific molecular mechanisms in different disease types offers potential for rapid improvements in outcome ...
Biankin, A.V. +27 more
core +3 more sources