Results 111 to 120 of about 2,360,733 (398)

Superparamagnetic Iron Oxide (SPIO)-enhanced Liver MR Imaging with Ferucarbotran [PDF]

, 2006
Die Superparamagnetic Iron Oxides (SPIO)-verstärkte MRT der Leber wird als sinnvolle präoperative diagnostische Methode mit einer hohen Sensitivität und Spezifität für die Detektion von fokalen Leberläsionen angewendet.
Namkung, Sook
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Deep learning CT reconstruction improves liver metastases detection

Insights into Imaging
Objectives Detection of liver metastases is crucial for guiding oncological management. Computed tomography through iterative reconstructions is widely used in this indication but has certain limitations.
Achraf Kanan, Bruno Pereira, Constance Hordonneau, Lucie Cassagnes, Eléonore Pouget, Léon Appolinaire Tianhoun, Benoît Chauveau, Benoît Magnin   +7 more
doaj   +1 more source

Colorectal cancer liver metastases organoids retain characteristics of original tumor and acquire chemotherapy resistance

Stem Cell Research, 2018
Background Colorectal cancer (CRC) liver metastasis is highly unfavorable for patient outcome and is a leading cause of cancer-related death. Pre-clinical research of CRC liver metastasis predominately utilizes CRC cell lines grown in tissue culture ...
Jon N. Buzzelli, D. Ouaret, Graham Brown, P. Allen, R. Muschel   +4 more
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Platelet Volume Is Reduced In Metastasing Breast Cancer: Blood Profiles Reveal Significant Shifts

Cancer Management and Research, 2019
Ming-ming Li,1,* Chen-xi Yue,1,* Shuang Fu,1 Xin Zhang,1 Chang-Jiu Zhao,2 Rui-tao Wang1 1Department of Internal Medicine, Harbin Medical University Cancer Hospital, Harbin Medical University, Harbin, Heilongjiang 150081, People’s Republic of China;
Li M, Yue C, Fu S, Zhang X, Zhao CJ, Wang R   +5 more
doaj  

Use of cytoceratin-20 in revealing of colorectal cancer metastases in liver [PDF]

Саратовский научно-медицинский журнал, 2013
The aim of the study is to evaluate the possibilities of immunohistochemical revealing of colorectal cancer micro-metastases in liver and to determine their prognostic significance. Material et metods.
Fedorina Т.A., Yugina 0.V., Vozdvijenski M.0.   +2 more
doaj  

Liver metastases in patients with curatively treated colorectal cancer

Сибирский онкологический журнал, 2019
Background. The problem of the development of liver metastases in colorectal cancer patients previously treated with curative intent surgery remains little studied. Identification of significant factors affecting the occurrence of metachronous metastasis
R. I. Rasulov, A. A. Yudin, G. I. Songolov   +2 more
doaj   +1 more source

Indication of Neoadjuvant Chemotherapy for Patients with Colorectal Cancer Liver Metastases in our Hospital [PDF]

, 2021
R. Kamimura, Tsuyoshi Kawai, Kohta Iguchi, Hiroaki Terajima   +3 more
openalex   +1 more source