Results 31 to 40 of about 311,004 (351)

Mouse models of colorectal cancer. [PDF]

, 2011
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip, Tong, Yunguang, Yang, Wancai   +2 more
core   +2 more sources

The varied clonal trajectory of liver and lung metastases of colorectal cancer

Advances in Cancer Biology - Metastasis
Background: The liver and lungs are the most common sites of colorectal cancer (CRC) metastases. Their involvement can take five different clinical scenarios: lung metastases only, liver metastases only, lung metastases before liver metastases, liver ...
Ofer N. Gofrit, Ben Gofrit, S. Nahum Goldberg, Aron Popovtzer, Jacob Sosna, Ayala Hubert   +5 more
doaj   +1 more source

Surgical treatment of stage IV colorectal cancer with synchronous liver metastases : a systematic review and network meta-analysis

, 2020
Background: The ideal treatment approach for colorectal cancer (CRC) with synchronous liver metastases (SCRLM) remains debated. We performed a network meta-analysis (NMA) comparing the 'bowel-first' approach (BFA), simultaneous resection (SIM), and the ...
Berardi, Giammauro, Ceelen, Wim, Ghiasloo, Mohammad, Pavlenko, Diana, Troisi, Roberto, Uyttebroek, Ortwin, Van Langenhove, Zoé, Verhaeghe, Marzia   +7 more
core   +1 more source

Hepatic resection for metastatic colorectal adenocarcinoma: A proposal of a prognostic scoring system [PDF]

, 1999
Background: Hepatic resection for metastatic colorectal cancer provides excellent longterm results in a substantial proportion of patients. Although various prognostic risk factors have been identified, there has been no dependable staging or prognostic ...
Bonham, AC, Dodson, F, Dvorchik, I, Fung, JJ, Gayowski, TJ, Geller, DA, Iwatsuki, S, Madariaga, JR, Starzl, TE, Wallis Marsh, J   +9 more
core   +1 more source

The impact of pulmonary metastasectomy in patients with previously resected colorectal cancer liver metastases. [PDF]

PLoS ONE, 2017
BACKGROUND:40-50% of patients with colorectal cancer (CRC) will develop liver metastases (CRLM) during the course of the disease. One third of these patients will additionally develop pulmonary metastases. METHODS:137 consecutive patients with CRLM, were
Armin Wiegering, Johannes Riegel, Johanna Wagner, Volker Kunzmann, Johannes Baur, Thorsten Walles, Ulrich Dietz, Stefan Loeb, Christoph-Thomas Germer, Ulrich Steger, Ingo Klein   +10 more
doaj   +1 more source

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI) [PDF]

, 2012
The objective of this pilot clinical study was to assess the safety, technical feasibility, pharmacokinetic (PK) profile and tumour response of DC Bead™ with irinotecan (DEBIRI™) delivered by intra-arterial embolisation for the treatment of metastatic ...
Eichler, Katrin, Gallus, Christof, Gruber-Rouh, Tatjana, Hammerstingl, Renate Maria, Mack, Martin G., Vogl, Thomas J., Zangos, Stephan   +6 more
core   +1 more source

Angiopoietin-2 blockade suppresses growth of liver metastases from pancreatic neuroendocrine tumors by promoting T cell recruitment

The Journal of Clinical Investigation, 2023
Improving the management of metastasis in pancreatic neuroendocrine tumors (PanNETs) is critical, as nearly half of patients with PanNETs present with liver metastases, and this accounts for the majority of patient mortality. We identified angiopoietin-2
Eunhyeong Lee, Sophie O’Keefe, Alessandra Leong, Ha-Ram Park, Janani Varadarajan, Subrata Chowdhury, Shannon Hiner, Sungsoo Kim, Anahita Shiva, Richard A. Friedman, Helen Remotti, Tito Fojo, Hee Won Yang, Gavin Thurston, Minah Kim   +14 more
doaj   +1 more source

Liver resections: complications and survival outcome [PDF]

, 2007
none1noToday, liver resection represents one of the most effective therapies in the treatment of defined liver diseases, particularly for hepatocellular carcinomas, liver metastases and tumors originating from the bile ducts.
Grazi, Gian Luca
core   +1 more source

Radiation therapy for primary carcinoma of the extrahepatic biliary system. An analysis of 63 cases. [PDF]

, 1991
From 1976 to 1988, 63 patients received radiation therapy for primary cancers of the extrahepatic biliary system (eight gallbladder and 55 extrahepatic biliary duct). Twelve patients underwent orthotopic liver transplantation.
Carr, BI, Epstein, AH, Flickinger, JC, Iwatsuki, S, Starzl, TE   +4 more
core   +1 more source

Risk factors for residual liver recurrence of colorectal cancer after resection of liver metastases and significance of adjuvant chemotherapy

Asian Journal of Surgery
Objective: The risk factors for residual liver recurrence after resection of colorectal cancer liver metastases were analyzed separately for synchronous and metachronous metastases.
Hiroko Sawano, Hiroshi Matsuoka, Tomohiro Mizuno, Tadahiro Kamiya, Yongchol Chong, Hideaki Iwama, Takeshi Takahara, Junichiro Hiro, Koki Otsuka, Takuma Ishihara, Takahiro Hayashi, Kouichi Suda   +11 more
doaj   +1 more source