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Characteristics of extracts from liver microsomes
Experimental Cell Research, 1957Abstract When rat liver microsomes are treated at 1–3 °C with 0.1–0.2 M bicarbonate buffer, pH 8.2–8.4, about 70 per cent of the ribonucleic acid is gradually released from the particles together with some protein. The extracted microsome residues can be largely brought into solution by treatment with deoxycholate or other detergents. The properties
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Human liver microsomal drug metabolism
Biochemical Pharmacology, 1970F J, Darby, W, Newnes, D A, Price Evans
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Activation of Thionophosphates by Liver Microsomes
Nature, 1959MANY organophosphorus insecticides are poor inhibitors of cholinesterase, but are converted to potent inhibitors (‘activated’) by certain mammalian and insect tissues. The activation by liver slices was first shown by Gardiner and Kilby1 for schradan (a phosphoroamidate), and by Diggle and Gage2 for parathion (a phosphorothionate). Davison3 showed that
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Oxidation of cycloalkenes in liver microsomes
Biochemical Pharmacology, 1971K C, Liebman, E, Ortiz
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The gut–liver axis and gut microbiota in health and liver disease
Nature Reviews Microbiology, 2023Cynthia Li-Shin Hsu, Bernd Schnabl
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Helenin inhibition of liver microsomal enzymes
Journal of Agricultural and Food Chemistry, 1982R R, Dalvi, C, McGowan
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Liver regeneration and inflammation: from fundamental science to clinical applications
Nature Reviews Molecular Cell Biology, 2021Lara Campana +2 more
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