Results 221 to 230 of about 1,906,831 (271)

Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.

Toxicology and Applied Pharmacology, 2015
Yoko Watanabe, Hiroyuki Kojima, S. Takeuchi, Naoto Uramaru, S. Sanoh, K. Sugihara, S. Kitamura, S. Ohta   +7 more
semanticscholar   +1 more source

In vitro metabolism of 2-ethylhexyldiphenyl phosphate (EHDPHP) by human liver microsomes.

Toxicology Letters, 2015
A. Ballesteros-Gómez, C. Erratico, N. Eede, Alin C Ionas, P. Leonards, A. Covaci   +5 more
semanticscholar   +1 more source

Benzydamine N-oxygenation as an index for flavin-containing monooxygenase activity and benzydamine N-demethylation by cytochrome P450 enzymes in liver microsomes from rats, dogs, monkeys, and humans.

Drug Metabolism and Pharmacokinetics, 2015
Tomomi Taniguchi-Takizawa, M. Shimizu, T. Kume, H. Yamazaki   +3 more
semanticscholar   +1 more source

Large‐scale multiplex absolute protein quantification of drug‐metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH‐MS: Comparison with MRM/SRM and HR‐MRM/PRM

Proteomics, 2016
Kenji Nakamura, Mio Hirayama-Kurogi, S. Ito, T. Kuno, Toshihiro Yoneyama, Wataru Obuchi, T. Terasaki, S. Ohtsuki   +7 more
semanticscholar   +1 more source

Biotransformation of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) by human liver microsomes: identification of cytochrome P450 2B6 as the major enzyme involved.

Chemical Research in Toxicology, 2013
C. Erratico, A. Szeitz, S. Bandiera
semanticscholar   +1 more source

Mechanistic insights from comparing intrinsic clearance values between human liver microsomes and hepatocytes to guide drug design.

European journal of medicinal chemistry, 2012
L. Di, C. Keefer, Dennis O. Scott, T. Strelevitz, G. Chang, Y. Bi, Yurong Lai, Jonathon Duckworth, K. Fenner, M. Troutman, R. Obach   +10 more
semanticscholar   +1 more source

Oxidation of cycloalkenes in liver microsomes

Biochemical Pharmacology, 1971
K C, Liebman, E, Ortiz
openaire   +2 more sources

Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes.

Life Science, 2011
Rongrong Jiang, Satoshi Yamaori, Shuso Takeda, I. Yamamoto, Kazuhito Watanabe   +4 more
semanticscholar   +1 more source

Simultaneous absolute quantification of 11 cytochrome P450 isoforms in human liver microsomes by liquid chromatography tandem mass spectrometry with in silico target peptide selection.

Journal of Pharmacy and Science, 2011
H. Kawakami, S. Ohtsuki, J. Kamiie, Takashi Suzuki, T. Abe, T. Terasaki   +5 more
semanticscholar   +1 more source

Oxidation of Indene in Liver Microsomes

Molecular Pharmacology, 1968
K C, Leibman, E, Ortiz
openaire   +2 more sources