Redox Biology, 2013 Acetaminophen (APAP) overdose is the most frequent cause of acute liver failure in the US and many western countries. It is well known that APAP induces mitochondrial damage to trigger centrilobular necrosis.
Hong-Min Ni +3 more
doaj +1 more source
Effects of thymol on non-alcholic hepatic liver induced with chronic immobility in rats
Armaghane Danesh Bimonthly Journal, 2021 Background and Aim: Considering the role of oxidative stress on non-alcoholic fatty liver disease and changing lipid profiles, the antioxidant effect of plants and fruits on biochemical indicators was investigated.
Somaye Miri +3 more
doaj
Protocol TOP-Study (tacrolimus organ perfusion): a prospective randomized multicenter trial to reduce ischemia reperfusion injury in transplantation of marginal liver grafts with an "ex vivo" tacrolimus perfusion [PDF]
, 2013 Background: Critical organ shortage results in the utilization of extended donor criteria (EDC) liver grafts. These marginal liver grafts are prone to increased ischemia reperfusion injury (IRI) which may contribute to deteriorated graft function and ...
Jauch, Karl-Walter +24 more
core +1 more source
Arquivos de Gastroenterologia, 2017 BACKGROUND Ischemia/reperfusion causes organ damage but it is mandatory in hepatic transplantation, trauma and other complex liver surgeries, when Pringle maneuver is applied to minimize bleeding during these procedures.
Emilio Elias ABDO +5 more
doaj +1 more source
Histologic variant form of autoimmune hepatitis with prominent zonal necrosis [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2002 Autoimmune hepatitis type 1 in a 8-year old girl is described. The diagnosis was established using International Autoimmune hepatitis group scoring system.
Stanković Ivica +3 more
doaj +1 more source
Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection [PDF]
, 2008 Autoimmune liver diseases, such as autoimmune hepatitis (AIH) and primary biliary cirrhosis, often have severe consequences for the patient. Because of a lack of appropriate animal models, not much is known about their potential viral etiology. Infection
Hintereder, Gudrun +23 more
core +1 more source
ISOLATED HYPERTHERMIC CHEMOPERFUSION OF THE LIVER IN ITS METASTATIC LESIONS
Вестник хирургии имени И.И. Грекова, 2018 OBJECTIVE. The aim of the study is to evaluate the clinical efficacy of isolated hyperthermic liver chemoperfusion with melphalan and tumor necrosis factor alpha when it is isolated bilobate metastatic lesion and the ineffectiveness of systemic ...
N. A. Maistrenko +7 more
doaj +1 more source
Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation [PDF]
, 1994 Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase.
Bechstein, W. O. +6 more
core
Hepatoprotective Effects of Against Carbon Tetrachloride-Induced Acute Liver Injury in Rats
Dose-Response, 2021 Purpose: To determine the hepatoprotective mechanisms of Heracleum candicans in rats with acute liver injury induced by carbon tetrachloride (CCl 4 ). Methods: Rats were intragastrically administered H candicans twice a day for 14 consecutive days and ...
Jie Li +6 more
doaj +1 more source
Clostridium perfringens types A and D associated with enterotoxemia in an 18-month-old goat
Journal of Venomous Animals and Toxins including Tropical Diseases, 2007 Postmortem examination of a Boer buck that died peracutely revealed bowel and liver diffusely congested and edematous. Kidney was apparently edematous. Clostridium perfringens type A was isolated from bowel and type D from kidney. Microscopic examination
S. Miyashiro +4 more
doaj +1 more source