Results 61 to 70 of about 418,078 (213)

Crystal Structure of Human TWEAK in Complex with the Fab Fragment of a Neutralizing Antibody Reveals Insights into Receptor Binding. [PDF]

, 2013
The tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a multifunctional cytokine playing a key role in tissue regeneration and remodeling.
Jens Niewoehner, Monika Baehner, Kohnert, Ulrich, Schraeml, Michael, Ulrich Kohnert, Alfred Lammens, Katja Lammens, Lammens, Katja, Karl-Peter Hopfner, Leopold von Proff, Lammens, Alfred, Hopfner, Karl-Peter, Niewoehner, Jens, Michael Schraeml, Baehner, Monika, Proff, Leopold von   +15 more
core   +1 more source

Anti-Tumor Necrosis Factor Therapy in Intestinal Behçet's Disease

, 2018
Intestinal Behçet's disease is a rare, immune-mediated chronic intestinal inflammatory disease; therefore, clinical trials to optimize the management and treatment of patients are scarce.
천재희, 박지혜
core   +1 more source

Selenium and Liver Necrosis in the Hyperthyroid Rat [PDF]

Nature, 1958
IT is well known that dietary deficiencies can be seriously aggravated by the induction of a hyperthyroid state. Recently it has been shown1–3 that selenium significantly prolongs the survival-time of rats and prevents the onset of the liver necrosis which follows the ingestion of a diet containing yeast as the only source of protein.
openaire   +2 more sources

Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure

FEBS Open Bio, 2014
Excessive acetaminophen (APAP) use is one of the most common causes of acute liver failure. Various types of cell death in the damaged liver are linked to APAP-induced hepatotoxicity, and, of these, necrotic cell death of hepatocytes has been shown to be
Kenji Takemoto, Etsuro Hatano, Keiko Iwaisako, Masatoshi Takeiri, Naruto Noma, Saori Ohmae, Kan Toriguchi, Kazutaka Tanabe, Hirokazu Tanaka, Satoru Seo, Kojiro Taura, Keigo Machida, Norihiko Takeda, Shigehira Saji, Shinji Uemoto, Masataka Asagiri   +15 more
doaj   +1 more source

Electric foot-shock stress drives TNF-alpha production in the liver of IL-6-deficient mice

, 2004
Objectives: Accumulating evidence has shown that interleukin-6 (IL-6) has pleiotropic effects on a variety of biological functions, including its antiapoptotic potential during liver injury.
Chida, Y, Motomura, Y, Kubo, C, Sudo, N
core  

Arrested Plasmodium liver stages as experimental anti-malaria vaccines.

, 2011
Eukaryotic pathogens typically follow a complex life cycle, including host switch and morphologically distinct forms. Parasite stage conversion offers exceptional opportunities for whole organism vaccine development.
Matuschewski, K., Hafalla, J., Matuschewski, Kai, Kai Matuschewski, Julius Clemence Hafalla, Friesen, J., Borrmann, Steffen, Johannes Friesen, Borrmann, S., Hafalla, Julius Clemence, Steffen Borrmann, Friesen, Johannes   +11 more
core   +1 more source

Histological Changes of Electric Yellow Cichlid (Labidochromis caeruleus) Exposed to Acute and Chronic Cadmium Concentrations

Turkish Journal of Agriculture: Food Science and Technology, 2019
In this study, electric yellow cichlid were (Labidochromis caeruleus) exposed to acute cadmium (Cd) concentrations (0, 50, 60, 70, 80 mg l-1) for 72 h, and chronic Cd concentrations (0.00, 0.25, 0.50, 1.00, 2.00 mg l-1) for 20 d to examine histological
Semra Küçük, Sema Midilli, Mehmet Güler, Deniz Çoban   +3 more
doaj   +1 more source

Therapeutic modulation of liver ischaemia reperfusion injury

, 2011
Liver Ischaemia Reperfusion Injury (IRI) leads to production of reactive oxygen species and cytokines, which affects hepatocellular function following liver resection and transplantation.
Sheth, H.
core  

Locally up-regulated lymphotoxin a, not systemic tumor necrosis factor a, is the principle mediator of murine cerebral malaria [PDF]

, 2002
Cerebral malaria (CM) causes death in children and nonimmune adults. TNF-{alpha} has been thought to play a key role in the development of CM. In contrast, the role of the related cyto-kine lymphotoxin {alpha} (LT{alpha}) in CM has been overlooked.
Sanjeet Sawhney, Mynott, T.L., Kaye, PM, De Souza, J Brian, Bickle, Quentin D, Kaye, P.M., Engwerda, C.R., Sawhney, Sanjeet, Engwerda, CR, Tracey L. Mynott, Paul M. Kaye, Christian R. Engwerda, Bickle, Q.D., Sawhney, S, Bickle, QD, Mynott, Tracey L, De Souza, JB, Mynott, TL, Engwerda, Christian R, Sawhney, S., J. Brian De Souza, Quentin D. Bickle, Kaye, Paul M, De Souza, J.B.   +23 more
core   +1 more source

Hepatoprotective activity of Clearliv a polyherbal formulation in Wistar rats

Archives of Medicine and Health Sciences, 2013
Objective: To evaluate the hepatoprotective activity of Clearliv a polyherbal formulation in Wistar rats. Materials and Methods: The hepatoprotective potential of Clearliv was evaluated in thioacetamide-induced liver necrosis, DL-galactosamine [GalN ...
E P Kumar, Vijay R Rajan, Anil D Kumar, S Parasuraman, S F Emerson   +4 more
doaj   +1 more source