Results 31 to 40 of about 151,195 (302)
Frontiers in Oncology, 2021 BackgroundIn this study, we designed a new (Su’S) target area delineation to protect the normal liver during liver regeneration and prospectively evaluate liver regeneration after radiotherapy, as well as to explore the clinical factors of liver ...
Ting-Shi Su +6 more
doaj +1 more source
Regeneration and Recovery after Acetaminophen Hepatotoxicity
Livers, 2023 Liver regeneration is a compensatory response to tissue injury and loss. It is known that liver regeneration plays a crucial role in recovery following acetaminophen (APAP)-induced hepatotoxicity, which is the major cause of acute liver failure (ALF) in ...
Bharat Bhushan, Udayan Apte
doaj +1 more source
Molecular and Cellular Biochemistry, 2006 Liver possesses the capacity to restore its tissue mass and attain optimal volume in response to physical, infectious and toxic injury. The extraordinary ability of liver to regenerate is the effect of cross-talk between growth factors, cytokines, matrix components and many other factors.
Pawlowski, Rafał, Jura, Jolanta
openaire +3 more sources
FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes
npj Regenerative Medicine, 2022 Upon injury, the liver is capable of substantial regeneration from the original tissue until an appropriate functional size. The underlying mechanisms controlling the liver regeneration processes are not well elucidated.
Chi-Qian Liang +13 more
doaj +1 more source
Data in Brief, 2017 This data contains information related to the research article entitled “Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis” [1].
Marco Antonio Briones-Orta +5 more
doaj +1 more source
Hepatocytes Polyploidization and Cell Cycle Control in Liver Physiopathology
International Journal of Hepatology, 2012 Most cells in mammalian tissues usually contain a diploid complement of chromosomes. However, numerous studies have demonstrated a major role of “diploid-polyploid conversion” during physiopathological processes in several tissues.
Géraldine Gentric +2 more
doaj +1 more source
Liver regeneration in traditional Chinese medicine: advances and challenges
Regenerative Medicine Research, 2020 Liver diseases pose a serious problem for national health care system all over the world. Liver regeneration has profound impacts on the occurrence and development of various liver diseases, and it remains an extensively studied topic.
Zhang Feng +7 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Mfap4: a promising target for enhanced liver regeneration and chronic liver disease treatment
npj Regenerative Medicine, 2023 The liver has a remarkable regenerative capacity. Nevertheless, under chronic liver-damaging conditions, this capacity becomes exhausted, allowing the accumulation of fibrotic tissue and leading to end-stage liver disease.
Viktoriia Iakovleva +9 more
doaj +1 more source