Results 11 to 20 of about 1,320,778 (302)
Clinical implications of advances in liver regeneration [PDF]
Clinical and Molecular Hepatology, 2015 Remarkable advances have been made recently in the area of liver regeneration. Even though liver regeneration after liver resection has been widely researched, new clinical applications have provided a better understanding of the process.
Yong Jin Kwon +2 more
doaj +3 more sources
Studies on the hyperplasia ('regeneration') of the rat liver following partial hepatectomy. Changes in lipid peroxidation and general biochemical aspects [PDF]
, 1990 Using the experimental model of partial hepatectomy in the rat, we have examined the relationship between cell division and lipid peroxidation activity. In rats entrained to a regime of 12 h light/12 h dark and with a fixed 8 h feeding period in the dark
Maddix, SP +9 more
core +7 more sources
Translational Research, 2014 The liver is unique in its ability to regenerate in response to injury. A number of evolutionary safeguards have allowed the liver to continue to perform its complex functions despite significant injury. Increased understanding of the regenerative process has significant benefit in the treatment of liver failure.
Shennen A. Mao +2 more
openaire +2 more sources
Journal of Hepatology, 2006 During liver regeneration after partial hepatectomy, normally quiescent hepatocytes undergo one or two rounds of replication to restore the liver mass by a process of compensatory hyperplasia. A large number of genes are involved in liver regeneration, but the essential circuitry required for ...
Fausto, Nelson +2 more
openaire +3 more sources
Liver Development, Regeneration, and Carcinogenesis [PDF]
, 2010 The identification of putative liver stem cells has brought closer the previously separate fields of liver development, regeneration, and carcinogenesis. Significant overlaps in the regulation of these processes are now being described.
Ross, James A +7 more
core +1 more source
Journal of Cellular Physiology, 2007 AbstractLiver regeneration after partial hepatectomy is a very complex and well‐orchestrated phenomenon. It is carried out by the participation of all mature liver cell types. The process is associated with signaling cascades involving growth factors, cytokines, matrix remodeling, and several feedbacks of stimulation and inhibition of growth related ...
openaire +2 more sources
PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells
Cell Death and Disease, 2021 To date, there is no representative in vitro model for liver sinusoidal endothelial cells (LSECs), as primary LSECs dedifferentiate very fast in culture and no combination of cytokines or growth factors can induce an LSEC fate in (pluripotent stem cell ...
Jonathan De Smedt +13 more
doaj +1 more source
Liver Regeneration and Cell Transplantation for End-Stage Liver Disease
Biomolecules, 2021 Liver transplantation is the only curative option for end-stage liver disease; however, the limitations of liver transplantation require further research into other alternatives.
Yan Li, Lungen Lu, Xiaobo Cai
doaj +1 more source
Cells, 2019 Hepatocytes are the main parenchymal cells of the liver and play important roles in liver homeostasis and disease process. The heterogeneity of normal hepatocytes has been reported, but there is little knowledge about hepatocyte subtype and distinctive ...
Na Chang +8 more
doaj +1 more source
Cell Death and Disease, 2023 Biliary atresia (BA) is a severe inflammatory and fibrosing neonatal cholangiopathy disease characterized by progressive obstruction of extrahepatic bile ducts, resulting in cholestasis and progressive hepatic failure.
Shen Yang +12 more
doaj +1 more source