Results 31 to 40 of about 148,295 (267)

Functional characterization of urine-derived stem cells from acute-on-chronic liver failure patients in an immune-mediated acute liver injury model

Frontiers in Bioengineering and Biotechnology
IntroductionAcute-on-chronic liver failure (ACLF) is a highly lethal clinical syndrome with limited effective therapeutic options. Urine-derived stem cells (USCs) represent a non-invasive and readily accessible cell source, but whether USCs obtained from
Jiateng Zhang, Jiateng Zhang, Pengfei Yu, Pengfei Yu, Jiaqi Li, Jiaqi Li, Xiao Lin, Rui Zhao, Rui Zhao, Huaibin Zou, Huaibin Zou, Yu Chen, Yu Chen, Yuanyuan Zhang, Zhongping Duan, Zhongping Duan   +15 more
doaj   +1 more source

A Prospective Study of Liver Regeneration After Radiotherapy Based on a New (Su’S) Target Area Delineation

Frontiers in Oncology, 2021
BackgroundIn this study, we designed a new (Su’S) target area delineation to protect the normal liver during liver regeneration and prospectively evaluate liver regeneration after radiotherapy, as well as to explore the clinical factors of liver ...
Ting-Shi Su, Li-Qing Li, Shi-Xiong Liang, Bang-De Xiang, Jian-Xu Li, Jia-Zhou Ye, Le-Qun Li   +6 more
doaj   +1 more source

Clinical value and safety of liver biopsy in patients with liver failure

BMC Gastroenterology
Background To evaluate the safety, etiological diagnostic value, and impact on clinical treatment decisions of transjugular liver biopsy (TJLB) and percutaneous liver biopsy (PLB) in patients with liver failure.
Jingran Jiao, Rui Zhao, Yongping Zhang, Manman Xu, Yu Chen   +4 more
doaj   +1 more source

FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes

npj Regenerative Medicine, 2022
Upon injury, the liver is capable of substantial regeneration from the original tissue until an appropriate functional size. The underlying mechanisms controlling the liver regeneration processes are not well elucidated.
Chi-Qian Liang, Deng-Cheng Zhou, Wen-Tao Peng, Wu-Yun Chen, Hai-Yan Wu, Yi-Min Zhou, Wei-Li Gu, Kyu-Sang Park, Hui Zhao, Long-Quan Pi, Li Zheng, Shan-Shan Feng, Dong-Qing Cai, Xu-Feng Qi   +13 more
doaj   +1 more source

Regeneration and Recovery after Acetaminophen Hepatotoxicity

Livers, 2023
Liver regeneration is a compensatory response to tissue injury and loss. It is known that liver regeneration plays a crucial role in recovery following acetaminophen (APAP)-induced hepatotoxicity, which is the major cause of acute liver failure (ALF) in ...
Bharat Bhushan, Udayan Apte
doaj   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita, Norma Candelaria López Santiago, Claudia Maria García Cuellar, Karla Maldonado Silva, Nancy Reynoso Noverón, Leticia Hernández Cadena   +5 more
wiley   +1 more source

Prediction of transcription factor bindings sites affected by SNPs located at the osteopontin promoter

Data in Brief, 2017
This data contains information related to the research article entitled “Osteopontin splice variants and polymorphisms in Cancer Progression and Prognosis” [1].
Marco Antonio Briones-Orta, S. Eréndira Avendaño-Vázquez, Diana Ivette Aparicio-Bautista, Jason D. Coombes, Georg F. Weber, Wing-Kin Syn   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The mystery of liver regeneration

British Journal of Surgery, 2002
Abstract Background Partial hepatectomy is the strongest stimulator of hepatic regeneration. The process of initiation and the control of the final size of the regenerated liver have been the subject of research for many years. A better understanding of this process and the effect of disease may allow
Court, F., Wemyss-Holden, S., Dennison, A., Maddern, G.   +3 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source