Results 21 to 30 of about 271,840 (313)
Cell Death and Disease, 2023 Biliary atresia (BA) is a severe inflammatory and fibrosing neonatal cholangiopathy disease characterized by progressive obstruction of extrahepatic bile ducts, resulting in cholestasis and progressive hepatic failure.
Shen Yang +12 more
doaj +1 more source
Intercellular communication in normal and regenerating rat liver: a quantitative analysis [PDF]
, 1981 We have compared intercellular communication in the regenerating and normal livers of weanling rats. The electrophysiological studies were conducted at the edge of the liver, and we have found that here as elsewhere in the liver there is a dramatic ...
Meyer, David J. +3 more
core +2 more sources
Hepatology Communications, 2020 It is well known that excessive cholesterol accumulation within hepatocytes deteriorates nonalcoholic fatty liver disease (NAFLD). Augmenter of liver regeneration (ALR) has been reported to alleviate NAFLD through anti‐apoptosis; however, whether ALR ...
Xin Wang +7 more
doaj +1 more source
Clinical implications of advances in liver regeneration [PDF]
Clinical and Molecular Hepatology, 2015 Remarkable advances have been made recently in the area of liver regeneration. Even though liver regeneration after liver resection has been widely researched, new clinical applications have provided a better understanding of the process.
Yong Jin Kwon +2 more
doaj +1 more source
Transcriptomic landscapes of effective and failed liver regeneration in humans
JHEP Reports, 2023 Background & Aims: Although extensive experimental evidence on the process of liver regeneration exists, in humans, validation is largely missing. However, liver regeneration is critically affected by underlying liver disease. Within this project, we
Patrick Starlinger +17 more
doaj +1 more source
MicroRNA-26b-5p Inhibits Mouse Liver Fibrogenesis and Angiogenesis by Targeting PDGF Receptor-Beta
Molecular Therapy: Nucleic Acids, 2019 Here microRNAs (miRNAs) with potentially therapeutic effects were screened and explored during liver fibrogenesis and angiogenesis via targeting the important mediators.
Le Yang +6 more
doaj +1 more source
Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]
, 2015 The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John +3 more
core +1 more source
The role of gut microbiota in liver regeneration
Frontiers in Immunology, 2022 The liver has unique regeneration potential, which ensures the continuous dependence of the human body on hepatic functions. As the composition and function of gut microbiota has been gradually elucidated, the vital role of gut microbiota in liver ...
Zhe Xu +9 more
doaj +1 more source
Small‐for‐size liver transplanted into larger recipient: A model of hepatic regeneration [PDF]
, 1994 Orthotopic liver transplantation was performed in 60 recipient rats weighing 200 to 250 gm. Sixty rats of the same strain were used as liver donors, 30 weighing 100 to 140 gm (small for size) and the other 30 weighing 200 to 250 gm (same size).
Carr, BI +7 more
core +1 more source
PPAR Research, 2015 It has been reported that bone marrow-derived mesenchymal stem cells (BMSCs) have capacity to migrate to the damaged liver and contribute to fibrogenesis in chronic liver diseases.
Xin Liu +6 more
doaj +1 more source