Results 21 to 30 of about 1,320,778 (302)

Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway

open access: yesHepatology Communications, 2020
It is well known that excessive cholesterol accumulation within hepatocytes deteriorates nonalcoholic fatty liver disease (NAFLD). Augmenter of liver regeneration (ALR) has been reported to alleviate NAFLD through anti‐apoptosis; however, whether ALR ...
Xin Wang   +7 more
doaj   +1 more source

MicroRNA-26b-5p Inhibits Mouse Liver Fibrogenesis and Angiogenesis by Targeting PDGF Receptor-Beta

open access: yesMolecular Therapy: Nucleic Acids, 2019
Here microRNAs (miRNAs) with potentially therapeutic effects were screened and explored during liver fibrogenesis and angiogenesis via targeting the important mediators.
Le Yang   +6 more
doaj   +1 more source

Transcriptomic landscapes of effective and failed liver regeneration in humans

open access: yesJHEP Reports, 2023
Background & Aims: Although extensive experimental evidence on the process of liver regeneration exists, in humans, validation is largely missing. However, liver regeneration is critically affected by underlying liver disease. Within this project, we
Patrick Starlinger   +17 more
doaj   +1 more source

The role of gut microbiota in liver regeneration

open access: yesFrontiers in Immunology, 2022
The liver has unique regeneration potential, which ensures the continuous dependence of the human body on hepatic functions. As the composition and function of gut microbiota has been gradually elucidated, the vital role of gut microbiota in liver ...
Zhe Xu   +9 more
doaj   +1 more source

A review of living donor liver transplantation: why is regeneration more rapid in the recipient compared to the donor? [PDF]

open access: yes, 2009
Includes bibliographical references (leaves 54-62).Living donor liver transplantation (LDLT) is now well established and performed on a routine basis in many major centres around the world.
Sheriff B Ibirogba, Ibirogba, Sheriff B
core   +1 more source

15-Deoxy-Δ12,14-Prostaglandin J2 Inhibits Homing of Bone Marrow-Derived Mesenchymal Stem Cells Triggered by Chronic Liver Injury via Redox Pathway

open access: yesPPAR Research, 2015
It has been reported that bone marrow-derived mesenchymal stem cells (BMSCs) have capacity to migrate to the damaged liver and contribute to fibrogenesis in chronic liver diseases.
Xin Liu   +6 more
doaj   +1 more source

The Role of Immune Cells in Liver Regeneration

open access: yesLivers, 2023
The liver is the only organ that can regenerate and regain its original tissue-to-body weight ratio within a short period of time after tissue loss.
Yankai Wen
doaj   +1 more source

Effect of sorafenib on murine liver regeneration [PDF]

open access: yes, 2011
Hepatocellular carcinoma (HCC) is a common cause of cancer-related death. Sorafenib prolongs survival of patients with advanced disease and is approved for the systemic treatment of unresectable HCC.
Pamela Romanque   +7 more
core   +1 more source

ALR and Liver Regeneration

open access: yesMolecular and Cellular Biochemistry, 2006
Liver possesses the capacity to restore its tissue mass and attain optimal volume in response to physical, infectious and toxic injury. The extraordinary ability of liver to regenerate is the effect of cross-talk between growth factors, cytokines, matrix components and many other factors.
Pawlowski, Rafał, Jura, Jolanta
openaire   +3 more sources

Overexpression of apolipoprotein A-I alleviates endoplasmic reticulum stress in hepatocytes

open access: yesLipids in Health and Disease, 2017
Background Abnormal lipid metabolism may contribute to an increase in endoplasmic reticulum (ER) stress, resulting in the pathogenesis of non-alcoholic steatohepatitis.
Qing Guo, Can Zhang, Yutong Wang
doaj   +1 more source

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