Results 161 to 170 of about 53,126,315 (234)

OsCPK12‐OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice

Advanced Science, EarlyView.
OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Beifang Wang, Aaron Chan, Yongyi Fan, Yanwu Wang, Pao Xue, Yingxin Zhang, Xiaodeng Zhan, Weixun Wu, Ping Yu, Daibo Chen, Junlin Fu, Yongbo Hong, Xihong Shen, Lianping Sun, Aike Zhu, Shihua Cheng, Qunen Liu, Liyong Cao   +17 more
wiley   +1 more source

Loss of CYLD on Chromosome 16q Impairs Homologous Recombination and Genomic Stability Through TIRR Degradation

Advanced Science, EarlyView.
Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu, Jialu Kang, Qi Ye, Zixi Wang, Lei Li, Yuzeshi Lei, Leihong Ye, Tianjie Liu, Bin Wang, Tao Liu, Shan Xu, Ke Wang, Yong Zhang, Jian Ma, Lei Li   +14 more
wiley   +1 more source

Plasma levels of antimicrobial peptide LL-37 as a biomarker of sleep quality in patients with obstructive sleep apnea: A clinical observational study. [PDF]

PLoS One
Yamaguchi T, Hosokawa K, Mineta T, Hosokawa R, Odawara S, Chiba R, Asanuma K, Toyomaki S, Sato M, Takahashi F, Sakurai S, Takahashi K, Nishijima T.   +12 more
europepmc   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Effects of Botulinum Toxin A on Rosacea-Like Inflammation in an LL-37-Induced Rosacea Mouse Model. [PDF]

Ann Dermatol
Yoon D, Lee JO, Jang YN, Yoo KH, Kim BJ, Choi SY.   +5 more
europepmc   +1 more source

Aggregation‐Controlled Triplet Exciton Regulation Enables Single‐Emitter Color‐Evolving Afterglow

Advanced Science, EarlyView.
A single‐emitter system based on DTP‐R luminophores enables time‐evolving afterglow through aggregation‐regulated excited‐state dynamics. The coexistence and suppression of delayed fluorescence and phosphorescence are controlled via concentration tuning and host‐guest engineering, revealing the RISC origin of delayed fluorescence and enabling ...
Yu Zhang, Zonghang Liu, Gian Albert Alfani, Xilong Wei, Yue Zhang, Ziyu Cui, Yi Lu, Yixuan Chen, Dan Liu, Lin Lu, Zihao Deng, Shuyu Xue, Parvej Alam, Zheng Zhao, Ben Zhong Tang   +14 more
wiley   +1 more source

Aggregation-State Dynamics Drive Double Cooperativity Between Antimicrobial Peptides LL-37 and HNP1. [PDF]

Angew Chem Int Ed Engl
Hou Y, Zhang J, Takeuchi K, Higuchi H, Kaya M, Li R, Zheng J, Chen J, Watanabe G, Sugihara K.   +9 more
europepmc   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

RNA selectively modulates activity of virulent amyloid PSMα3 and host-defense LL-37 via phase separation and aggregation dynamics. [PDF]

Elife
Rayan B, Barnea E, Indig R, Pantoja CF, Gayk J, Lupu-Haber Y, Upcher A, Argoetti A, Larsen JA, Buell AK, Zweckstetter M, Landau M.   +11 more
europepmc   +2 more sources

Heteroaggregation of Antimicrobial Peptides LL-37 and HNP‑1 Drives Cooperative Neutralization of Cytotoxicity. [PDF]

JACS Au
Zhang J, Hou Y, Yasuda T, Chow SYA, Ito S, Otsuka M, Ikeuchi Y, Li X, Sugihara K.   +8 more
europepmc   +1 more source