Results 111 to 120 of about 188,935 (276)

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Effects of the antimicrobial peptide LL-37 in combination with hyperthermic preconditioning on the outcome of septic rats [PDF]

, 2008
Summary Background: We studied the effects of LL-37 prophylaxis or therapy on the outcome after intra-abdominal sepsis and tested whether additional preconditioning with fever-range hyperthermia augments host immune response and improves survival ...
Gurschi, Eugeniu
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease

BMC Gastroenterology, 2017
Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity.
Diana Hoang-Ngoc Tran, Jiani Wang, Christina Ha, Wendy Ho, S. Anjani Mattai, Angelos Oikonomopoulos, Guy Weiss, Precious Lacey, Michelle Cheng, Christine Shieh, Caroline C. Mussatto, Samantha Ho, Daniel Hommes, Hon Wai Koon   +13 more
doaj   +1 more source

Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. [PDF]

, 2019
Endovascular infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a major health care concern, especially infective endocarditis (IE).
Abdelhady, Wessam, Bayer, Arnold S, Chambers, Henry F, Ersoy, Selvi C, Li, Liang, Xiong, Yan Q   +5 more
core  

Expression and Modulation of LL-37 in Normal Human Keratinocytes, HaCaT cells, and Inflammatory Skin Diseases [PDF]

, 2005
Defensins and cathelicidins (LL-37) are major antimicrobial peptides (AMPs) of the innate immune system of the human skin. In normal non-inflamed skin these peptides are negligible, but their expression can be markedly increased in inflammatory skin ...
Alice, Beom Joon Kim, Byung In Ro, Chang Kwun Hong, Dorschner, Dorschner, Frohm, Fulton, Gallo, Grossman, Harder, Harder, Ji Eun Kim, Kim, Koczulla, Larrick, Leung, Mi Sook Jeong, Murakami, Murakami, Myeung Nam Kim, Nizet, Nizet, Ong, Park, Pivarcsi, Seo, Seong Jun Seo, Woo, Yang, Yang, Zaiou, Zanetti   +32 more
core   +2 more sources

Το αντιμικροβιακό πεπτίδιο LL-37 στη στοματική κοιλότητα [PDF]

, 2021
Το αντιμικροβιακό πεπτίδιο LL-37 αποτελεί σημαντικό μόριο της φυσικής ανοσίας στο στοματικό περιβάλλον. Σκοπός της διδακτορικής διατριβής ήταν ο προσδιορισμός της σιελικής συγκέντρωσης του αντιμικροβιακού πεπτιδίου LL-37 καθώς και η διερεύνηση παραγόντων που πιθανώς σχετίζονται με αυτήν. Για το λόγο αυτό, έγινε λήψη ολικού σάλιου από 203 άτομα, με καλή
openaire   +1 more source

Testing a Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

Arthritis Care &Research, EarlyView.
Objective We aimed to test the efficacy of personalized treatment of older veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABCs) as compared with usual care (UC). Methods Two hundred ninety‐nine veterans aged 65 to 89 with CLBP from three Veterans Affairs (VA) medical centers underwent baseline testing, randomization to ABC ...
Debra K. Weiner, Angela Gentili, Meika A. Fang, Edward Garay, Laura Lawson, Lenore Joseph, Cathy C. Lee, Michelle I. Rossi, Beverly Thorn, Subashan Perera   +9 more
wiley   +1 more source

Construction and Expression of Recombinant LL-37 as Histag-SUMO Fusion Protein with Factor Xa Cleavage Site

Hayati Journal of Biosciences
LL-37 is an antimicrobial protein expressed by the CAMP gene in humans. This protein has various antibacterial, antiviral and anticancer effects. Expressing LL-37 as a heterologous protein in E. coli cells has its challenges.
Tina Rostinawati, Imam Adi Wicaksono, Bernap Dwi Putra Sitinjak, Muhammad Fadhlillah   +3 more
doaj   +1 more source