Results 131 to 140 of about 56,247,789 (275)

LL-18 and FF-18 effectively inhibit EV71 infection.

open access: yes
(A-D) Cell viability of RD cells treated with the indicated amount of DL-37 (A), LL-37 (B), LL-18 (C), or FF-18 (D) was plotted against peptide concentration, and the cytotoxicity was determined.
Hang Yang (577653)   +10 more
core   +1 more source

Proposed model of LL-37 induced mutagenesis.

open access: yes, 2014
At sub-inhibitory concentrations, LL-37 can penetrate P. aeruginosa cells and enter the bacterial cytosol, where LL-37 dimers then bind to DNA. DNA binding by LL-37 then promotes DinB-dependent replication, which potentiates mutations in mucA leading to ...
Benjamin T. Kopp (555327)   +6 more
core   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

open access: yesAdvanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag   +3 more
wiley   +1 more source

Overcoming the Trade‐Off Between Magnetic Coupling and Electrical Insulation in Soft Magnetic Materials via Nanochain Engineering

open access: yesAdvanced Science, EarlyView.
This study employs a nanochain engineering approach combined with an in situ oxidation strategy to fabricate self‐insulating iron‐based magnetic nanochains, addressing the challenge of balancing magnetic coupling and electrical insulation in soft magnetic materials.
Dingrong Zuo   +8 more
wiley   +1 more source

Proteína 3 contendo um domínio NACHT, porção C-terminal rica em repetições de leucina e de domínio pirina e LL-37: valor prognóstico de novos biomarcadores em pneumonia adquirida na comunidade

open access: yesJornal Brasileiro de Pneumologia
RESUMO Objetivo Este estudo teve como objetivo determinar os níveis séricos de proteína 3 contendo um domínio NACHT, porção C-terminal rica em repetições de leucina e de domínio pirina (NLRP3) e catelicidina LL-37, bem como investigar sua importância ...
Chuanan Zhu   +4 more
doaj   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang   +18 more
wiley   +1 more source

LL-37 promotes expression of IL-1β by human and murine myeloid cells in a P2X7R-independent manner.

open access: yes, 2019
A and B) Primary human blood-derived monocytes were isolated, pretreated with 10 ng/ml E. coli 0111:B4 LPS for 3 hours, then exposed for 1 hour to 50 μg/ml LL-37, 5 mM ATP or untreated.
Hsin-Ni Li (6585674)   +12 more
core   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

open access: yesAdvanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang   +7 more
wiley   +1 more source

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

open access: yesAdvanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao   +19 more
wiley   +1 more source

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