Results 111 to 120 of about 191,557 (278)

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Combined Process‐ and Phase‐Field‐Simulation to Predict the Microstructure of Single‐Crystal Ni‐Based Superalloys

Advanced Engineering Materials, EarlyView.
A combined finite element and phase‐field approach predicts the evolution of microstructure during the directional solidification of Ni‐based superalloys. The model reveals how withdrawal rate, temperature gradient, and wall thickness control the dendrite spacing, highlighting the strong effect of surface regions in thin sections where dendrite growth ...
Sean Böhm, André B. Baldissera, Rainer Völkl, Uwe Glatzel   +3 more
wiley   +1 more source

Antimicrobial peptides: agents of border protection for companion animals. [PDF]

, 2012
Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K, Bevins, Charles L, Leonard, Brian C   +2 more
core   +1 more source

Το αντιμικροβιακό πεπτίδιο LL-37 στη στοματική κοιλότητα [PDF]

, 2021
Το αντιμικροβιακό πεπτίδιο LL-37 αποτελεί σημαντικό μόριο της φυσικής ανοσίας στο στοματικό περιβάλλον. Σκοπός της διδακτορικής διατριβής ήταν ο προσδιορισμός της σιελικής συγκέντρωσης του αντιμικροβιακού πεπτιδίου LL-37 καθώς και η διερεύνηση παραγόντων που πιθανώς σχετίζονται με αυτήν. Για το λόγο αυτό, έγινε λήψη ολικού σάλιου από 203 άτομα, με καλή
openaire   +1 more source

Numerical Modeling of Tank Cars Carrying Hazardous Materials With and Without Composite Metal Foam

Advanced Engineering Materials, EarlyView.
Large‐scale puncture models consisting of hazardous materials (HAZMATs) tank car with protective steel–steel composite metal foam (S–S CMF) are solved numerically. Tank car plate with added 10.91–13.33 mm thick S–S CMF layer does not puncture. Protective S–S CMF absorbs impact energy, reduces plate deformation, and prevents shear bands formation ...
Aman Kaushik, Afsaneh Rabiei
wiley   +1 more source

Numerical Exploration of Thermal Shock Resistance in MgO–C Refractories

Advanced Engineering Materials, EarlyView.
A mesostructure‐resolved numerical framework is developed to evaluate the thermal shock resistance of MgO–C refractories. By modeling interface debonding under rapid temperature changes and introducing a modified thermal shock parameter that accounts for mesocracks, the study shows how graphite content and aggregate size influence thermal shock ...
Jishnu Vinayak Gopi, Stephan Roth, Christos G. Aneziris, Bjoern Kiefer   +3 more
wiley   +1 more source

Construction and Expression of Recombinant LL-37 as Histag-SUMO Fusion Protein with Factor Xa Cleavage Site

Hayati Journal of Biosciences
LL-37 is an antimicrobial protein expressed by the CAMP gene in humans. This protein has various antibacterial, antiviral and anticancer effects. Expressing LL-37 as a heterologous protein in E. coli cells has its challenges.
Tina Rostinawati, Imam Adi Wicaksono, Bernap Dwi Putra Sitinjak, Muhammad Fadhlillah   +3 more
doaj   +1 more source

Activation of Eosinophils Interacting with Bronchial Epithelial Cells by Antimicrobial Peptide LL-37: Implications in Allergic Asthma

Scientific Reports, 2017
The role of antimicrobial peptide LL-37 in asthma exacerbation is unclear. Microbial infection, which is the most common inducer of asthma exacerbation, is accompanied by elevated LL-37.
Delong Jiao, Chun-Kwok Wong, Miranda Sin-Man Tsang, Ida Miu-Ting Chu, Dehua Liu, Jing Zhu, Man Chu, Christopher Wai-Kei Lam   +7 more
doaj   +1 more source

Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease

BMC Gastroenterology, 2017
Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity.
Diana Hoang-Ngoc Tran, Jiani Wang, Christina Ha, Wendy Ho, S. Anjani Mattai, Angelos Oikonomopoulos, Guy Weiss, Precious Lacey, Michelle Cheng, Christine Shieh, Caroline C. Mussatto, Samantha Ho, Daniel Hommes, Hon Wai Koon   +13 more
doaj   +1 more source

Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection. [PDF]

, 2019
Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. We investigated relevant phenotype differences between cfr-positive and -negative MRSA that contribute to pathogenesis, and the efficacy of linezolid-based combination ...
Li, Liang, Liao, Xiao-Ping, Liu, Ya-Hong, Sun, Jian, Tao, Meng-Ting, Xiong, Yan Q, Zhou, Yu-Feng   +6 more
core