Results 21 to 30 of about 57,467,955 (246)
Elevated levels of the antimicrobial peptide LL-37 in hidradenitis suppurativa are associated with a Th1/Th17 immune response. [PDF]
, 2018 Hidradenitis suppurativa (HS) is an inflammatory skin disease with poorly understood immunopathogenic mechanisms. LL-37 is an antimicrobial peptide, which is transcribed from the CAMP (cathelicidin antimicrobial peptide) gene.
Nikhil Yawalkar +17 more
core +3 more sources
Fluctuating role of antimicrobial peptide hCAP18/LL-37 in oral tongue dysplasia and carcinoma [PDF]
, 2020 Oral tongue squamous cell carcinoma (OTSCC), the most common cancer in the oral cavity, is aggressive and its incidence is increasing globally. Human host defense cationic antimicrobial peptide‑18/antimicrobial peptide leucine‑leucine‑37 (hCAP18/LL‑37 ...
Risteli, Maija +6 more
core +1 more source
Evaluating the Antiviral Activities of Human Cathelicidin LL-37 Peptide Against Rotavirus in Vitro
The Journal of Qazvin University of Medical Sciences, 2019 Background Rotavirus is the most prevalent cause of severe gastroenteritis, hospitalizations, and deaths among infants and young children, globally. No specific antiviral drug is available against rotavirus infection. Objective The current study aimed
Zohreh Hosseini +3 more
doaj +1 more source
Pathogenic nontuberculous mycobacteria resist and inactivate cathelicidin: implication of a novel role for polar mycobacterial lipids. [PDF]
PLoS ONE, 2015 Nontuberculous mycobacteria (NTM) are a large group of environmental organisms with worldwide distribution, but only a relatively few are known to be pathogenic.
Jennifer R Honda +8 more
doaj +1 more source
Effects of LL-37 on Gingival Fibroblasts: A Role in Periodontal Tissue Remodeling?
Vaccines, 2018 Mounting evidence suggests that the host defence peptide, LL-37, plays a role in both inflammation and in wound healing; however, the role of this peptide in the remodeling and maintenance of oral tissues is not yet fully understood.
Maelíosa T. C. McCrudden +3 more
doaj +1 more source
Gut Microbes, 2021 Clostridioides difficile infection is currently the leading cause of nosocomial antibiotic-associated diarrhea and pseudomembranous colitis worldwide. Cathelicidins, a major group of natural antimicrobial peptides, have antimicrobial and immunomodulatory
Banglao Xu, Xianan Wu, Yi Gong, Ju Cao
doaj +1 more source
Sequence and the expression construct of SP-LL-37.
, 2017 (A) Nucleotide sequence of SP-LL-37 containing the coding region and stop codon as well as the signal peptide (underlined). (B) Schematic diagram of the expression construct pSP1::SP-LL-37. Detection of Nos gene copy numbers in the T0 generation of pPZP::
Md. Amdadul Huq (3829780) +6 more
core +1 more source
Human antimicrobial peptide LL-37 contributes to Alzheimer’s disease progression
, 2022 s a prime mover in Alzheimer’s disease (AD), microglial activation requires membrane translocation, integration, and activation of the metamorphic protein chloride intracellular channel 1 (CLIC1), which is primarily cytoplasmic under physiological ...
Mazzanti, Michele +18 more
core +1 more source
Effects of LL-37 Peptide Mimetics on Gingival Fibroblast Function
, 2012 Effects of LL-37 Peptide Mimetics on Gingival Fibroblast Function Host defence peptides, including the cathelicidin LL-37, play an important role in mucosal immunity, functioning as both antimicrobial agents and modulators of the inflammatory response ...
Coulter, Wilson +3 more
core +2 more sources
, 2023 The basis of the present study is a straightforward method involving fewer chemical species for conjugating gold nanoparticles (AuNPs) with the antimicrobial peptide LL-37 designated as LL-37@AuNPs. Investigating the microstructure characteristics of the
Agung Setiawan +4 more
core +1 more source