Results 141 to 150 of about 7,152 (243)

Phase separation as an emerging regulatory framework in antibody class switching and genome stability. [PDF]

Front Immunol
Refaat AM, Shimizu H, Yasuhara T.
europepmc   +1 more source

Agreement of the performance of equine electrocardiogram recording devices for ECG complexity analysis

Equine Veterinary Journal, Volume 58, Issue 5, Page 1336-1344, September 2026.
Abstract Background Non‐linear equine electrocardiography (ECG) analysis is an actively developing study area which has the potential to lead to novel, artificial intelligence‐based diagnostic tools in equine cardiology. As more ECG recording devices are becoming available, there is a need to ensure results are interchangeable regardless of the ...
Vadim Alexeenko, Dhruvpal Singh Anchan, Fe Ter Woort, Caroline Ribonnet, Emmanuele van Erck, Celia Marr, Kamalan Jeevaratnam   +6 more
wiley   +1 more source

Programmable DNA Folding Modulates Phase Behavior and Dynamics of DNA/Peptide Condensates. [PDF]

ACS Nano
Katzir I, Wen Y, Razi I, Skoi V, Beck R, Dong H, Lampel A.   +6 more
europepmc   +1 more source

Origin of the ionic-strength dependent reentrant behavior in the liquid-liquid phase separation of uncharged intrinsically disordered proteins. [PDF]

Commun Chem
Mondal S, Shakhnovich E.
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, Volume 13, Issue 43, 3 August 2026.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Liquid-liquid phase separation in cancer therapy resistance. [PDF]

iScience
Hu P, Ding H, Yue N, Ye J, Ruan S, Qian Y, Wang C, Song D.   +7 more
europepmc   +1 more source

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, Volume 13, Issue 43, 3 August 2026.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

Liquid-liquid phase separation-related gene signature characterizes prognostic subtypes and therapeutic sensitivities in gastric cancer. [PDF]

Transl Cancer Res
Yan B, Lao Q, Lin L.
europepmc   +1 more source

Oligopeptides/DNA Coacervate Droplets as Macromolecular Delivery Microcarriers

Advanced Science, Volume 13, Issue 44, 7 August 2026.
Oligopeptide–DNA coacervates formed via liquid–liquid phase separation serve as programmable carriers for macromolecular cargos, entering cells through lipid raft–associated pathways and subsequently undergoing enzyme triggered intracellular disassembly driven by DNA degradation processes, thereby enabling efficient, controlled, and spatially defined ...
Linyi Zhang, Chong Wang, Mengqi Han, Yi Yang, Teng Ma, Luoran Shang   +5 more
wiley   +1 more source

RNA-binding protein family diversification correlates with neural complexity across metazoan evolution. [PDF]

iScience
Yasuda K.
europepmc   +1 more source