Results 151 to 160 of about 7,152 (243)

Exploring the Burden on Patients Living With and Receiving Treatment for Immune Thrombocytopenia (ITP): Patient and Physician Perceptions From the ITP World Impact Survey (I‐WISh) 2.0

American Journal of Hematology, Volume 101, Issue 8, Page 1954-1968, August 2026.
ABSTRACT Limited data exist on how patients and physicians perceive immune thrombocytopenia (ITP) symptoms and treatment‐related burden. I‐WISh (ITP World Impact Survey) 2.0 surveyed 1018 patients and 431 physicians in 15 countries to characterize the impact of ITP and its treatments on patients.
Nichola Cooper, James Bussel, Waleed Ghanima, Drew Provan, Yoshiaki Tomiyama, Ming Hou, Donald M. Arnold, Cristina Santoro, Francesco Zaja, Barbara Lovrencic, Mervyn Morgan, Michal Winograd, Jennifer DiRaimo, Danielle Boyle, Olivera Rajkovic‐Hooley, Meritxell Vendranas, Susan Frade, Caroline Kruse   +17 more
wiley   +1 more source

Relationship Between Filament-Polymerizing Muscle Myosin and Droplets Generated by Liquid-Liquid Phase Separation. [PDF]

Chembiochem
Waizumi T, Kikumoto M, Matsumoto T, Takiguchi K.   +3 more
europepmc   +1 more source

The Inertness of the Lysozyme Template: Assessing the Structural Impact of Silicification Byproducts and Precursors

Chemistry–Methods, Volume 6, Issue 8, August 2026.
Lysozyme templates bioinspired silicification via localized electrostatic pooling, at variance with disordered peptides, require counterion‐driven coacervation. Small‐angle X‐ray scattering and NMR spectroscopy reveal that the folded lysozyme template remains structurally inert and monomeric in the presence of silicic acid mimics and alcohol byproducts.
Tozivepi Aaron Munyayi, Francesco Bruno, Letizia Fiorucci, Vincenzo Mangini, Francesco Scattarella, Cinzia Giannini, Jose Malanho Da Silva, Giacomo Parigi, Angelo Gallo, Enrico Ravera   +9 more
wiley   +1 more source

Beyond a Metabolite: Lactylation as a Pivotal Regulator of Colorectal Cancer Pathogenesis and Treatment Resistance

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
This review elucidates how lactylation, a novel histone modification driven by lactate, regulates colorectal cancer pathogenesis. We summarize its roles in tumor progression, metastasis, stemness, immunosuppression, and therapy resistance, and discusses the promising therapeutic strategies of targeting the lactylation pathway.
Shuilan Yao, Yun Liang, Xinwen Liang, Qisheng Su, Xiaohong Li   +4 more
wiley   +1 more source

Modulation of Biomolecular Aggregate Morphology and Condensate Infectivity. [PDF]

Biomolecules
Ferreon JC, Choi KJ, Quan MD, Tsoi PS, Ferreon CC, Coskun U, Liao SJ, Ferreon ACM.   +7 more
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, Volume 40, Issue 8, Page 4845-4857, August 2026.
ABSTRACT Over the last decade, ashwagandha ( Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source

Elastic enhancer network tunes equilibrium thermodynamics of liquid liquid phase separation in super enhancers. [PDF]

iScience
Guo T, Zhang N, Li Y, Hao S, Liu J, Zhang L.   +5 more
europepmc   +1 more source

Exploring the BICC1 Interactome in HEK293T Cells: Insights Into RNA‐Mediated Protein Networks and Biomolecular Condensates

FASEB BioAdvances, Volume 8, Issue 8, August 2026.
Workflow for BICC1 interactome characterization in HEK293T cells. Cells expressing FLAG‐tagged BICC1 (full‐length or ΔSAM) were subjected to co‐immunoprecipitation under RNA‐preserved (−) or RNase‐treated (+) conditions (1). Interacting proteins were identified by LC–MS/MS (2) and analyzed through protein–protein interaction networks and functional ...
Heloísa Monteiro do Amaral‐Prado, Gabriela Alves Moreira, Cristiane Santos, Fernando Henrique Bosso, Felipe Eduardo Ciamponi, Guilherme Oliveira Barbosa, Mario Henrique Bengtson, Katlin Brauer Massirer   +7 more
wiley   +1 more source

Liquid-liquid phase separation in neural development. [PDF]

Cell Mol Life Sci
Surini S, de Curtis I.
europepmc   +1 more source

Advances in the nanostructure characterization of biological hydrogels formed by the prion‐like domain of EARLY FLOWERING 3

Acta Crystallographica Section D, Volume 82, Issue 8, Page 940-946, August 2026.
In biological systems, hydrogels often arise through liquid–liquid phase separation, where biomolecular condensates can age into gel‐like states. SAXS is a key technique to probe the molecular organization of these samples. This study introduces an in‐vacuum Gel‐Cell for SAXS‐based structural analysis of a biologically derived hydrogel formed by the ...
Stephanie Hutin, Pedro L. O. Filho, Anton M. Popov, Petra Pernot, Chloe Zubieta, Mark D. Tully   +5 more
wiley   +1 more source