Results 41 to 50 of about 117,740 (287)

A general weak nonlinearity model for LNAs [PDF]

, 2008
This paper presents a general weak nonlinearity model that can be used to model, analyze and describe the distortion behavior of various low noise amplifier topologies in both narrowband and wideband applications.
Annema, Anne Johan, Cheng, Wei, Croon, Jeroen A., Klaassen, Dirk B.M., Nauta, Bram   +4 more
core   +2 more sources

The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions

Angewandte Chemie, EarlyView.
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi, Jake Brill, Sanne Roumans, Amal Mathai, John D. Brennan, Yingfu Li   +5 more
wiley   +2 more sources

Polymerase-directed synthesis of C5-ethynyl locked nucleic acids [PDF]

, 2010
Modified nucleic acids have considerable potential in nanobiotechnology for the development of nanomedicines and new materials. Locked nucleic acid (LNA) is one of the most prominent nucleic acid analogues reported so far and we herein for the first time
Alemdaroglu, Battersby, Birte Vester, Burley, Condon, Dewey, Feldkamp, Gebeyehu, Gourlain, Harsha V. Burri, Held, Hocek, Hollenstein, Jager, Jepsen, Jesper Wengel, Koshkin, Kuwahara, Langer, Latham, Nieuwlandt, Obika, Obika, Patrick J. Hrdlicka, Pawan K. Sharma, Pawan Kumar, Perrin, Petrie, Piccirilli, Rakesh N. Veedu, Sakthivel, Santoro, Sau, Sawai, Singh, Srivatsan, Switzer, Tarasow, Tarasow, Thoresen, Vaish, Vaught, Vaught, Veedu, Veedu, Veedu, Veedu, Veedu, Veedu, Veedu, Weisbrod, Wengel, Wengel, Østergaard   +53 more
core   +1 more source

Design a low-noise 5GHz wideband microwave power amplifier using 90nm CMOS technology with area reduction employing an active inductor

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ
Systems that rely on wireless technology frequently use radio frequency integrated circuits (RFICs). Modern wireless communication systems rely heavily on low-noise amplifiers, particularly those operating in the 5 GHz frequency spectrum using 90nm ...
Taha Naufal Fadhil , A.Z. Yonis
doaj   +1 more source

Amplification and Re-Generation of LNA-Modified Libraries

Molecules, 2012
Locked nucleic acids (LNA) confer high thermal stability and nuclease resistance to oligonucleotides. The discovery of polymerases that accept LNA triphosphates has led us to propose a scheme for the amplification and re-generation of LNA-containing ...
Jesper Wengel, Birte Vester, Lykke H. Hansen, Rakesh N. Veedu, Holger Doessing   +4 more
doaj   +1 more source

Cryogenic MMIC low noise amplifiers [PDF]

, 2000
Monolithic (MMIC) and discrete transistor (MIC) low noise amplifiers are compared on the basis of performance, cost, and reliability. The need for cryogenic LNA’s for future large microwave arrays for radio astronomy is briefly discussed and data is ...
Erickson, N., Fernandez, J.E., Gaier, T., Weinreb, S., Wielgus, J.   +4 more
core   +1 more source

Locked nucleic acid inhibits amplification of contaminating DNA in real-time PCR

BioTechniques, 2005
Locked nucleic acid (LNA®) is a modified DNA with increased binding affinity for complementary DNA sequences. Our strategy was to use this property of LNA to inhibit undesired PCR amplification (e.g., from contaminating genomic DNA) in a cDNA-based assay.
Lone Hummelshoj, Lars P. Ryder, Hans O. Madsen, Lars K. Poulsen   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Efficient reverse transcription using locked nucleic acid nucleotides towards the evolution of nuclease resistant RNA aptamers. [PDF]

PLoS ONE, 2012
BACKGROUND: Modified nucleotides are increasingly being utilized in the de novo selection of aptamers for enhancing their drug-like character and abolishing the need for time consuming trial-and-error based post-selection modifications.
Lucile Crouzier, Camille Dubois, Stacey L Edwards, Lasse H Lauridsen, Jesper Wengel, Rakesh N Veedu   +5 more
doaj   +1 more source

Preparation and Study of Solid Lipid Nanoparticles Based on Curcumin, Resveratrol and Capsaicin Containing Linolenic Acid

Pharmaceutics, 2022
Linolenic acid (LNA) is the most highly consumed polyunsaturated fatty acid found in the human diet. It possesses anti-inflammatory effects and the ability to reverse skin-related disorders related to its deficiency.
Roberta Cassano, Simona Serini, Federica Curcio, Sonia Trombino, Gabriella Calviello   +4 more
doaj   +1 more source