Results 61 to 70 of about 37,721 (200)

Upregulated liver conversion of α-linolenic acid to docosahexaenoic acid in rats on a 15 week n-3 PUFA-deficient diets⃞

open access: yesJournal of Lipid Research, 2007
We quantified incorporation rates of plasma-derived α-linolenic acid (α-LNA, 18:3n-3) into “stable” liver lipids and the conversion rate of α-LNA to docosahexaenoic acid (DHA, 22:6n-3) in male rats fed, after weaning, an n-3 PUFA-adequate diet (4.6% α ...
Miki Igarashi   +5 more
doaj   +1 more source

Universal hybridization using LNA (locked nucleic acid) containing a novel pyrene LNA nucleotide monomer

open access: yes, 2001
A novel pyrene LNA nucleotide monomer is shown to mediate universal hybridization when incorporated into a DNA strand or a 2′-OMe-RNA/LNA chimeric strand.
Babu, Bolle Ravindra, Wengel, J.
core   +1 more source

Inhibition of EGF Uptake by Nephrotoxic Antisense Drugs In Vitro and Implications for Preclinical Safety Profiling

open access: yesMolecular Therapy: Nucleic Acids, 2017
Antisense oligonucleotide (AON) therapeutics offer new avenues to pursue clinically relevant targets inaccessible with other technologies. Advances in improving AON affinity and stability by incorporation of high affinity nucleotides, such as locked ...
Annie Moisan   +17 more
doaj   +1 more source

First Detection of Outflowing Gas in the Outskirts of the Broad-line Region in 1H 0707−495

open access: yesThe Astronomical Journal
We use near-infrared spectroscopy covering simultaneously the zJHK bands to look for outflowing gas from the nuclear environment of 1H 0707−495 taking advantage that this region is dominated by low-ionization broad-line region lines, most of them ...
Alberto Rodríguez-Ardila   +4 more
doaj   +1 more source

High Performance Low Noise Amplifier for Operations in Lower ISM Band [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2019
Increasing wireless standards pushes the limits on the nonlinearity of the receivers. The mobile devices, being battery operated forces the power constrains on the design of RF receivers.
MECWAN Akash, DEVAHSRAYEE N. M.
doaj  

Amino-LNA, Thio-LNA and Alpha-L-Oxy-LNA

open access: yes, 2004
Pub. No.: WO/2004/046160 International Application No.: PCT/DK2003/000788 Publication Date: 03.06.2004 International Filing Date: 18.11.2003 Chapter 2 Demand Filed: 08.06.2004 IPC: A61K 31/7088 (2006.01)A novel class of pharmaceuticals which ...
Pedersen, Daniel Sejer   +8 more
core  

Codesign of ${K}$ a-Band Integrated GaAs PIN Diodes Limiter and Low Noise Amplifier

open access: yesIEEE Access, 2019
In this paper, a novel concurrent design of integrated PIN-diode based limiter and low noise amplifier (LNA) is presented for Ka-band MMICs fabricated using a combined PIN/0.15-μm-pHEMT technology.
Lin Yang   +5 more
doaj   +1 more source

Efficient Enzymatic Synthesis of LNA-modified DNA duplexes using KOD DNA polymerase

open access: yes, 2009
Three different LNA-nucleoside triphosphates, LNA-TTP, LNA-ATP and LNA-5-methyl-CTP, were investigated as substrates for KODDNA polymerase. The results reveal that KODDNA polymerase is an efficient catalyst for template directed synthesis of ...
Veedu, Rakesh N.   +5 more
core   +1 more source

Design of a low noise amplier for a X-band phased array radar system in SiGe BiCMOS technology [PDF]

open access: yes, 2022
A LNA is the first active stage of a radio frequency receiver module, with the prevalent goal of minimizing the noise figure of the whole system. This work presents the design of two narrow-band LNA and a wide-band LNA for phased array radar applications.
Vanin, Marco
core  

Targeting LDL Cholesterol With LNA

open access: yesMolecular Therapy - Nucleic Acids, 2012
Cardiovascular disease is the number one cause of death in the industrialized world. Much of the morbidity and mortality from heart disease can be linked to elevated low-density lipoprotein (LDL) cholesterol, and one of the key genes that increases LDL cholesterol is Proprotein convertase subtilisin/kexin type 9 (PCSK9).
openaire   +3 more sources

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