Results 71 to 80 of about 23,272 (196)

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Codesign of ${K}$ a-Band Integrated GaAs PIN Diodes Limiter and Low Noise Amplifier

IEEE Access, 2019
In this paper, a novel concurrent design of integrated PIN-diode based limiter and low noise amplifier (LNA) is presented for Ka-band MMICs fabricated using a combined PIN/0.15-μm-pHEMT technology.
Lin Yang, Lin-An Yang, Taotao Rong, Yang Li, Zhi Jin, Yue Hao   +5 more
doaj   +1 more source

Wee1 kinase differentially regulates maize CDKA2;1a and CDKB1;1

The FEBS Journal, EarlyView.
In eukaryotes, Wee1 kinase inhibits the kinase activity of CDK/Cyc complexes through phosphorylation of a conserved residue in the CDK moiety. Wee1 is also present in plants, but has been scarcely studied. We have studied maize Wee1 regulation of CDKA/CycD2;2a or CDKB/CycD2;2a complexes.
Mingyar N. López‐Hernández, Estefany D. Guerrero‐Molina, Ulises Martínez‐Ortega, Aurora Lara‐Núñez, Jorge M. Vázquez‐Ramos   +4 more
wiley   +1 more source

Working So Hard: Double‐Stranded RNAs That Can Perform Both Gene Activation and Gene Silencing

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Working so hard: STING saRNAs are capable of not only entering the nucleus to induce subsequent target gene upregulation, but can also act as an siRNA to perform gene silencing. Chemical modifications in saRNA guide and passenger strands affect the strength of gene activation or gene silencing activity.
Virginia Wing‐Nam Chiu, Matthew Lawrence Hammill, Marwah Elabed, Sierra Varley, Yulia Lomonosova, Joseph Hoare, Jon Voutila, Henrik Hansen, Troels Koch, Jean‐Paul Desaulniers   +9 more
wiley   +1 more source

Training Preschool Staff to Collect Descriptive Assessment Data Using a Decision‐Making Model

Behavioral Interventions, Volume 41, Issue 3, July 2026.
ABSTRACT Function‐based interventions are commonly employed by behavioral practitioners to address challenging behavior sometimes displayed by individuals with autism spectrum disorder (ASD). To select a function‐based intervention for implementation, practitioners first need conduct a functional behavior assessment (FBA).
Nicholas A. Lindgren, Devanio J. Cousins, Thomas S. Higbee, Mina Mendoza, Mattie Mecham   +4 more
wiley   +1 more source

Tumour‐macrophage crosstalk initiated by NFIC/METTL3 negative feedback loop via exosomal miR‐194‐5p promotes NSCLC progression

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
NFIC/METTL3 negative feedback loop in NSCLC cells suppresses exosomal miR‐194‐5p via m6A methylation; reduced miR‐194‐5p deepresses ZNF106 in macrophages, promoting M2 polarization and IL‐6 secretion; Macrophage‐derived IL‐6 activates JAK2/STAT3 in NSCLC cells to upregulate METTL3, forming a positive feedback loop.
Shu Fang, Mingyue Hao, Han Meng, Yuhang Jiang, Qiwen Li, Jiao Liang, Xiaolu He, Yi Hu, Linling Zhou, Qianrun Wang, Qiyuan Zhuo, Ji Wu, Kesong Shi   +12 more
wiley   +1 more source

A K-Band RF-MEMS-Enabled Reconfigurable and Multifunctional Low-Noise Amplifier Hybrid Circuit

Active and Passive Electronic Components, 2011
A K-band (18–26.5 GHz) RF-MEMS-enabled reconfigurable and multifunctional dual-path LNA hybrid circuit (optimised for lowest/highest possible noise figure/linearity, resp.) is presented, together with its subcircuit parts.
R. Malmqvist, C. Samuelsson, A. Gustafsson, P. Rantakari, S. Reyaz, T. Vähä-Heikkilä, A. Rydberg, J. Varis, D. Smith, R. Baggen   +9 more
doaj   +1 more source

Intrinsic Functional Architecture Reflects Individual Differences in Passive Working Memory: An Exploratory Resting‐State fMRI Study

Human Brain Mapping, Volume 47, Issue 10, July 2026.
Passive working memory performance is associated with intrinsic connectivity among dorsal attention, control, and sensorimotor subnetworks, suggesting a baseline functional scaffolding for individual differences. ABSTRACT Passive working memory (WM) is rarely detectable because it is thought to rely less on persistent neural firing, leaving a minimal ...
Yun Tian, Jiangtao Chen, Ziyuan Li, Li Gong, Qiang Liu   +4 more
wiley   +1 more source

Increased Expression of miR‐326 Mediates Chemosensitivity in Pediatric Acute Lymphoblastic Leukemia Through ABCA2 and YY1 Downregulation: An Observational and Experimental Study

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Multidrug resistance (MDR) is a major determinant of relapse‐associated mortality in pediatric acute lymphoblastic leukemia (pALL). Although miR‐326 downregulation has been associated with poor prognosis, its role in chemoresistance remains undefined. This study investigated the mechanistic contribution of miR‐326 to MDR in
Narges Aberuyi, Soheila Rahgozar, Melika Katebi   +2 more
wiley   +1 more source

Gain-Boosted X-Band GaN Low-Noise Amplifier MMIC With Y/preZ-Embedding Network

IEEE Access
This study improves the performance of an X-band gallium nitride (GaN) low-noise amplifier (LNA) using a gain-boosting embedding network. Using a gain-plane graph, analytical expressions are derived from the Z-parameters of the transistor to determine ...
In Hyuk Song, Seong Hee Han, Youn Sub Noh, Jong Won Lim, Dong Wook Kim   +4 more
doaj   +1 more source