Results 81 to 90 of about 23,328 (215)

Diagnostic potential of B‐cell translocation gene 2 in IgA nephropathy: Insights from molecular mechanisms

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Diagnostic value of BTG2 and its immunoregulatory mechanism in IgAN. This study reveals that BTG2 improves immune microenvironment dysregulation, attenuates inflammation, and reduces fibrosis by promoting the expansion of T follicular helper cells, inducing macrophage polarization toward an M2 anti‐inflammatory phenotype, and inhibiting the TGF‐β1 ...
Min Kou, Mo Dan, Juan Cheng, Sheng Ge, Ruimin Ren   +4 more
wiley   +1 more source

MicroRNA‐Driven Regulation of β‐Cell Function in Type 2 Diabetes: Molecular Mechanisms, Network Insights, and Translational Perspectives

Acta Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT MicroRNAs (miRNAs) have emerged as central regulators of pancreatic islet biology, influencing β‐cell development, proliferation, and function. In type 2 diabetes (T2D), both adaptive and maladaptive miRNA responses shape β‐cell compensation and progressive secretory dysfunction.
Lena Eliasson, Alexandros Karagiannopoulos, Mototsugu Nagao, Anna Wendt   +3 more
wiley   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

Advanced Engineering Materials, Volume 28, Issue 15, 5 August 2026.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele, Hossein Ipakchi, Tizazu H. Mekonnen   +2 more
wiley   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

An approach to low noise amplifier optimization in Advanced Design System CAD

Безопасность информационных технологий, 2016
An approach to silicon low noise amplifier (LNA) optimization, intended for use in the CAD Advanced Design System, has been presented. The approach is based on a technique using the contour plots of LNA parameters such as operating current, transistor ...
Galina Nikolaevna Nazarova, Vadim Vladimirovich Elesin, Denis Ivanovich Sotskov   +2 more
doaj  

MicroRNAs in Spinal Cord Injury: Molecular and Translational Insights

Brain and Behavior, Volume 16, Issue 8, August 2026.
MicroRNAs (miRNAs) modulate secondary injury cascades following spinal cord injury (SCI), including inflammation, oxidative stress, apoptosis, and demyelination. Key miRNAs such as miR‐21, miR‐124, miR‐219, and miR‐223 exert neuroprotective effects by regulating astrocytic response, axon regeneration, and remyelination.
Seyyedeh Fahimeh Talebi, Hossein Kalarestaghi, Ehsan Sheikh Hesabi, Saeed Vafaei‐Nezhad   +3 more
wiley   +1 more source

Targeting Spatiotemporal Heterogeneity of oncomiRNAs: A New Frontier in Cancer Therapy

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background miRNAs are short RNA transcripts that modulate gene expression after transcription and have emerged as pivotal regulators of cancer biology. A subset, termed oncomiRNAs, functions as oncogenes or tumor suppressors, influencing key cellular events such as cell growth, programmed cell death, neovascularization, tissue invasion, and ...
T. Jeethy Ram, Muralee Damodaran
wiley   +1 more source

CMOS low noise amplifier design trends towards millimeter-wave IoT sensors

Ain Shams Engineering Journal
Millimeter Wave (mm-wave) technology is a prerequisite to ensure ubiquitous wireless communication, given the rapid growth of the Internet of Things (IoT) infrastructure that integrates emerging technologies such as virtual reality (VR), artificial ...
Mohammad Arif Sobhan Bhuiyan, Md Rownak Hossain, Mohammad Shahriar Khan Hemel, Mamun Bin Ibne Reaz, Khairun Nisa' Minhad, Tan Jian Ding, Mahdi H. Miraz   +6 more
doaj   +1 more source

Livestock Depredations and Prevention Strategies to Foster Human‐Carnivore Coexistence in Western Mongolia's High Mountain Systems

Ecology and Evolution, Volume 16, Issue 8, August 2026.
The implementation of visual deterrents (i.e., Foxlights) proved to be effective in reducing the number of night‐time livestock depredations by both snow leopards and wolves. ABSTRACT The decline of large carnivores and the overabundance of livestock practices contribute significantly to ecosystem degradation.
Marcello Franchini, Charleen Gavette, Rodney Jackson, Kayley Bateman, Ashleigh Lutz‐Nelson, Geraldine Werhahn, Yelik Nurbat, Marco Zaccaroni, Fabio Dartora, Munkhtsog Bayaraa, Claudio Augugliaro   +10 more
wiley   +1 more source

Partitioning Site Amplification and κ0 in Earthquake Recordings

Earthquake Spectra, Volume 42, Issue 3, August 2026.
This study explores site amplification and spectral decay (κ0) estimates, focusing on the challenge of separating the two in observed Fourier amplitude spectra (FAS). We apply two general approaches: a Bayesian broadband inversion for simultaneous estimation of site amplification and κ0, and slope‐based methods for direct κ0 estimation from the ...
Bartik Pandel, Ellen M. Rathje, Alexandros Savvaidis, Albert R. Kottke   +3 more
wiley   +1 more source