Results 51 to 60 of about 23,328 (215)
The Journal of Pathology, EarlyView.Abstract Benign prostatic hyperplasia (BPH) is the most common urologic disease in aging men, resulting in significant morbidity. The etiologies of BPH are unknown, though chronic prostatic inflammation is known to promote hyperplasia, fibrotic remodeling, and therapeutic resistance in BPH.
Nadia A Lanman +12 more
wiley +1 more source
Predictive efficacy of low burden EGFR mutation detected by next-generation sequencing on response to EGFR tyrosine kinase inhibitors in non-small-cell lung carcinoma. [PDF]
PLoS ONE, 2013 Direct sequencing remains the most widely used method for the detection of epidermal growth factor receptor (EGFR) mutations in lung cancer; however, its relatively low sensitivity limits its clinical use.
Hye Sook Kim +17 more
doaj +1 more source
SusMat, EarlyView.A defect‐rich TiO2−x nanolayer was simultaneously synthesized and nano‐anchored on a mesoporous bio‐silica (diatomite) through a rapid, low‐temperature atmospheric‐pressure plasma process in aqueous media. The optimized TiO2−x/bio‐silica composite (DE 700) exhibits oxygen vacancies, an anatase–rutile heterointerface, broad solar‐spectrum absorption ...
Ali M. Abou‐Elanwar +14 more
wiley +1 more source
Molecular Therapy: Nucleic Acids, 2012 We report the structure activity relationships of short 14-mer phosphorothioate gapmer antisense oligonucleotides (ASOs) modified with α-L-locked nucleic acid (LNA) and related modifications targeting phosphatase and tensin homologue (PTEN) messenger RNA
Punit P Seth +5 more
doaj +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
VIEW, EarlyView.Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source
Journal of Vinyl and Additive Technology, EarlyView.The curing process of epoxidized soybean oil (ESO) is feasible through the incorporation of amino acids, generating materials with greater thermal stability and improved environmental friendliness. ABSTRACT In this study, the curing and thermal degradation kinetics of epoxidized soybean oil (ESO) were investigated using L‐aspartic acid (AA) and DL ...
Nicole P. Soares +6 more
wiley +1 more source
International Journal of Urban and Regional Research, EarlyView.Abstract This article develops the concept of environmental statecraft to study changing urban environmental politics in China and beyond. Our review of existing conceptions reveals a growing need to account for temporal and geographical complexity. Neoliberal conceptions of eco‐state restructuring are increasingly strained by contemporary geopolitical
Handuo Deng, Fulong Wu, Fangzhu Zhang
wiley +1 more source
First Detection of Outflowing Gas in the Outskirts of the Broad-line Region in 1H 0707−495
The Astronomical JournalWe use near-infrared spectroscopy covering simultaneously the zJHK bands to look for outflowing gas from the nuclear environment of 1H 0707−495 taking advantage that this region is dominated by low-ionization broad-line region lines, most of them ...
Alberto Rodríguez-Ardila +4 more
doaj +1 more source
Journal of Lipid Research, 2007 We quantified incorporation rates of plasma-derived α-linolenic acid (α-LNA, 18:3n-3) into “stable” liver lipids and the conversion rate of α-LNA to docosahexaenoic acid (DHA, 22:6n-3) in male rats fed, after weaning, an n-3 PUFA-adequate diet (4.6% α ...
Miki Igarashi +5 more
doaj +1 more source