Results 11 to 20 of about 63,220 (230)

RLF-LPI: An ensemble learning framework using sequence information for predicting lncRNA-protein interaction based on AE-ResLSTM and fuzzy decision

Mathematical Biosciences and Engineering, 2022
Long non-coding RNAs (lncRNAs) play a regulatory role in many biological cells, and the recognition of lncRNA-protein interactions is helpful to reveal the functional mechanism of lncRNAs.
Jinmiao Song, Shengwei Tian, Long Yu, Qimeng Yang , Qiguo Dai , Yuanxu Wang, Weidong Wu, Xiaodong Duan   +7 more
doaj   +1 more source

LPIH2V: LncRNA-protein interactions prediction using HIN2Vec based on heterogeneous networks model

Frontiers in Genetics, 2023
LncRNA-protein interaction plays an important role in the development and treatment of many human diseases. As the experimental approaches to determine lncRNA–protein interactions are expensive and time-consuming, considering that there are few ...
Meng-Meng Wei, Chang-Qing Yu, Li-Ping Li, Li-Ping Li, Zhu-Hong You, Zhong-Hao Ren, Yong-Jian Guan, Xin-Fei Wang, Yue-Chao Li   +8 more
doaj   +1 more source

LncRNA expression profile in human malignant embryonic rhabdomyosarcoma cell line infected with Coxsackie virus group B type 5 [PDF]

Jichu yixue yu linchuang, 2022
Objective To explore the molecular mechanism of the interaction between Coxsackie virus group B type 5 (CVB5) and the host, The long non-coding RNA(lncRNA) expression profile in human malignant embryonic rhabdomyosarcoma cell line (RD) infected by CVB5 ...
TENG Pei-ying, LI Jing, SHI Yu-lu, YANG Fan, OU Xia, CHEN Wei
doaj   +1 more source

SGII: Systematic Identification of Essential lncRNAs in Mouse and Human Genome With lncRNA-Protein-Protein Heterogeneous Interaction Network

Frontiers in Genetics, 2022
Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Xiao-Hong Xin, Ying-Ying Zhang, Chu-Qiao Gao, Hui Min, Likun Wang, Pu-Feng Du   +5 more
doaj   +1 more source

Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks

Frontiers in Genetics, 2023
Background: Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs.
Yuzhou Ma, Han Zhang, Chen Jin, Chuanze Kang   +3 more
doaj   +1 more source

The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]

, 2020
[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida, Cerdán, María Esperanza, Lamas, Mónica, Quindós-Varela, María, Rodríguez-Belmonte, Esther, Salamini-Montemurri, Martín, Vizoso-Vázquez, Ángel   +6 more
core   +1 more source

Predicting lncRNA–Protein Interactions With miRNAs as Mediators in a Heterogeneous Network Model

Frontiers in Genetics, 2020
Long non-coding RNAs (lncRNAs) play important roles in various biological processes, where lncRNA–protein interactions are usually involved. Therefore, identifying lncRNA–protein interactions is of great significance to understand the molecular functions
Yuan-Ke Zhou, Zi-Ang Shen, Han Yu, Tao Luo, Yang Gao, Pu-Feng Du   +5 more
doaj   +1 more source

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

Revealing protein-lncRNA interaction [PDF]

, 2015
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs are often able to bind a large number of different RNAs.
Colantoni, A, Ferrè, F, Helmer-Citterich, M   +2 more
core   +1 more source

PRPI-SC: an ensemble deep learning model for predicting plant lncRNA-protein interactions

BMC Bioinformatics, 2021
Background Plant long non-coding RNAs (lncRNAs) play vital roles in many biological processes mainly through interactions with RNA-binding protein (RBP).
Haoran Zhou, Jael Sanyanda Wekesa, Yushi Luan, Jun Meng   +3 more
doaj   +1 more source