Results 41 to 50 of about 64,353 (185)
Genome Biology, 2023 Background Extensive studies have revealed the function and mechanism of lncRNAs in development and differentiation, but the majority have focused on those lncRNAs adjacent to protein-coding genes.
Pei Lu +9 more
doaj +1 more source
Multi-feature fusion for deep learning to predict plant lncRNA-protein interaction
Genomics, 2020 Long non-coding RNAs (lncRNAs) play key roles in regulating cellular biological processes through diverse molecular mechanisms including binding to RNA binding proteins. The majority of plant lncRNAs are functionally uncharacterized, thus, accurate prediction of plant lncRNA-protein interaction is imperative for subsequent functional studies.
Jael Sanyanda, Wekesa +2 more
openaire +2 more sources
Fusing multiple protein-protein similarity networks to effectively predict lncRNA-protein interactions [PDF]
BMC Bioinformatics, 2017 Long non-coding RNA (lncRNA) plays important roles in many biological and pathological processes, including transcriptional regulation and gene regulation. As lncRNA interacts with multiple proteins, predicting lncRNA-protein interactions (lncRPIs) is an important way to study the functions of lncRNA. Up to now, there have been a few works that exploit
Xiaoxiong Zheng +6 more
openaire +3 more sources
Kidney Diseases, 2022 Aim: The aim of this study was to investigate the role and mechanism of long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3)-205 in renal inflammation and fibrosis in diabetic nephropathy (DN). Materials and Methods: lncRNA microarray profiling
Qimei Luo +9 more
doaj +1 more source
Gene Ontology-based function prediction of long non-coding RNAs using bi-random walk
BMC Medical Genomics, 2018 Background With the development of sequencing technology, more and more long non-coding RNAs (lncRNAs) have been identified. Some lncRNAs have been confirmed that they play an important role in the process of development through the dosage compensation ...
Jingpu Zhang, shuai Zou, Lei Deng
doaj +1 more source
Divergent lncRNAs take the lead on pluripotent cell differentiation [PDF]
, 2016 [No abstract ...
Ballarino, Monica, Rosa, Alessandro
core +1 more source
The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation [PDF]
, 2018 The expression of the long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is largely deregulated in epithelial cancers and positively correlates with poor prognosis and progression of hepatocellular carcinoma and gastrointestinal cancers.
A Busanello +51 more
core +1 more source
The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA [PDF]
, 2016 Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells.
Bozzoni, Irene +8 more
core +5 more sources
Altered long noncoding RNA profile after intracerebral hemorrhage
Annals of Clinical and Translational Neurology, 2019 Objective We investigated the expression pattern of long noncoding RNAs (lncRNA) and messenger RNAs (mRNA) from two different intracerebral hemorrhage (ICH) rat models, and performed gene ontology and gene/protein interaction analyses.
Jeong‐Min Kim +6 more
doaj +1 more source
Integrated analyses of long noncoding RNAs and mRNAs in the progression of breast cancer
Journal of International Medical Research, 2021 Objective The objective was to explore the expression and potential functions of long noncoding RNA (lncRNA) and mRNAs in human breast cancer (BC). Methods Differentially expressed lncRNAs and mRNAs were identified and annotated in BC tissues by using ...
Jingyun Guo +6 more
doaj +1 more source