Conservation and losses of avian non-coding RNA loci [PDF]
arXiv, 2014 Here we present the results of a large-scale bioinformatic annotation of non-coding RNA loci in 48 avian genomes. Our approach uses probabilistic models of hand-curated families from the Rfam database to infer conserved RNA families within each avian genome. We supplement these annotations with predictions from the tRNA annotation tool, tRNAscan-SE and
arxiv
miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer [PDF]
, 2012 Katarzyna Augoff +3 more
openalex +1 more source
Heterogeneous network and graph attention auto-encoder for LncRNA-disease association prediction [PDF]
arXivThe emerging research shows that lncRNAs are associated with a series of complex human diseases. However, most of the existing methods have limitations in identifying nonlinear lncRNA-disease associations (LDAs), and it remains a huge challenge to predict new LDAs.
arxiv
Estimating robustness of the tileShuffle method with repeated probes [PDF]
arXiv, 2014 In this paper the TileShuffle method is evaluated as a search method for candidate lncRNAs at 8q24.2. The method is run on three microarrays. Microarrays which all contained the same sample and repeated copies of tiled probes. This allows the coherence of the selection method within and between microarrays to be estimated by Monte Carlo simulations on ...
arxiv
Antisense Transcript Long Noncoding RNA (lncRNA) HOTAIR is Transcriptionally Induced by Estradiol [PDF]
, 2013 Arunoday Bhan +5 more
openalex +1 more source
Perspectives of LncRNAs for therapy
Cell Biology and Toxicology, 2022 Ilieva, Mirolyuba, Uchida, Shizuka
openaire +3 more sources
Noncoding RNAs in Host–Microbiota Interaction
Animal Research and One Health, EarlyView.The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao +7 more
wiley +1 more source
Cell Cycle-Related lncRNAs as Innovative Targets to Advance Cancer Management
Cancer Management and Research, 2023 Xiao-Ru Liang,1,* Yan-Fei Liu,1,* Feng Chen,2 Zhi-Xia Zhou,3 Li-Jie Zhang,1 Zhi-Juan Lin1 1Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Weifang
Liang XR +5 more
doaj
LoRA-BERT: a Natural Language Processing Model for Robust and Accurate Prediction of long non-coding RNAs [PDF]
arXivLong non-coding RNAs (lncRNAs) serve as crucial regulators in numerous biological processes. Although they share sequence similarities with messenger RNAs (mRNAs), lncRNAs perform entirely different roles, providing new avenues for biological research.
arxiv
Down with ncRNA! Long live fRNA and jRNA! [PDF]
arXiv, 2017 Noncoding RNA (ncRNA) and long noncoding RNA (lncRNA) are scientifically invalid terms because they define molecular entities according to properties they do not possess and functions they do not perform. Here, I suggest retiring these two terms. Instead, I suggest using an evolutionary classification of genomic function, in which every RNA molecule is
arxiv